Functional Dynamics of Deuterated β 2 ‐Adrenergic Receptor in Lipid Bilayers Revealed by NMR Spectroscopy

G‐protein‐coupled receptors (GPCRs) exist in conformational equilibrium between active and inactive states, and the former population determines the efficacy of signaling. However, the conformational equilibrium of GPCRs in lipid bilayers is unknown owing to the low sensitivities of their NMR signal...

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Veröffentlicht in:	Angewandte Chemie International Edition 2014-12, Vol.53 (49), p.13376-13379
Hauptverfasser:	Kofuku, Yutaka, Ueda, Takumi, Okude, Junya, Shiraishi, Yutaro, Kondo, Keita, Mizumura, Takuya, Suzuki, Shiho, Shimada, Ichio
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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