Comprehensive Step-by-Step Engineering of an (R)-Hydroxynitrile Lyase for Large-Scale Asymmetric Synthesis

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Veröffentlicht in:Angewandte Chemie International Edition 2003-10, Vol.42 (39), p.4815-4818
Hauptverfasser: Glieder, Anton, Weis, Roland, Skranc, Wolfgang, Poechlauer, Peter, Dreveny, Ingrid, Majer, Sandra, Wubbolts, Marcel, Schwab, Helmut, Gruber, Karl
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container_title Angewandte Chemie International Edition
container_volume 42
creator Glieder, Anton
Weis, Roland
Skranc, Wolfgang
Poechlauer, Peter
Dreveny, Ingrid
Majer, Sandra
Wubbolts, Marcel
Schwab, Helmut
Gruber, Karl
description
doi_str_mv 10.1002/anie.200352141
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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Acetonitriles - chemistry
asymmetric synthesis
C-C coupling
Chlorine - chemistry
enzyme catalysis
Glycosylation
Hydro-Lyases - chemical synthesis
Models, Molecular
Mutagenesis, Site-Directed
Nitriles - chemical synthesis
Pichia
protein design
protein engineering
Saccharomyces cerevisiae
title Comprehensive Step-by-Step Engineering of an (R)-Hydroxynitrile Lyase for Large-Scale Asymmetric Synthesis
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