Manganese(I)‐Catalyzed Highly Enantioselective Synthesis of Aziridine Phosphines

Herein, we present the first catalytic asymmetric nucleophilic addition of diarylphosphines to 2H‐azirines, facilitated by a chiral Mn(I) complex. This method not only provides access to novel class of derivatives of the aziridine core—a structural motif recognized for its antitumor and antibacterial properties—but also introduces a phosphine moiety alongside the generation of an NH moiety within a strained three‐membered ring. The discovery of this new Mn(I) complex that both enables the reaction and induces stereoselectivity is pivotal, as it underscores the significant potential of this earth‐abundant metal in advancing asymmetric catalysis.