Ethanol: Unlocking an Abundant Renewable C 2 ‐Feedstock for Catalytic Enantioselective C−C Coupling
With annual production at >85 million tons/year, ethanol is the world's largest‐volume renewable small molecule carbon source, yet its use as a C 2 ‐feedstock in enantioselective C−C coupling is unknown. Here, the first catalytic enantioselective C−C couplings of ethanol are demonstrated in...
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| Veröffentlicht in: | Angewandte Chemie 2021-05, Vol.133 (19), p.10636-10640 |
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| container_end_page | 10640 |
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| container_issue | 19 |
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| container_title | Angewandte Chemie |
| container_volume | 133 |
| creator | Meyer, Cole C. Stafford, Nicholas P. Cheng, Melinda J. Krische, Michael J. |
| description | With annual production at >85 million tons/year, ethanol is the world's largest‐volume renewable small molecule carbon source, yet its use as a C
2
‐feedstock in enantioselective C−C coupling is unknown. Here, the first catalytic enantioselective C−C couplings of ethanol are demonstrated in reactions with structurally complex, nitrogen‐rich allylic acetates incorporating the top 10 N‐heterocycles found in FDA‐approved drugs. |
| doi_str_mv | 10.1002/ange.202102694 |
| format | Article |
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| ispartof | Angewandte Chemie, 2021-05, Vol.133 (19), p.10636-10640 |
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| language | eng |
| recordid | cdi_crossref_primary_10_1002_ange_202102694 |
| source | Wiley Online Library - AutoHoldings Journals |
| title | Ethanol: Unlocking an Abundant Renewable C 2 ‐Feedstock for Catalytic Enantioselective C−C Coupling |
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