Pretreatment with intraventricular basic fibroblast growth factor decreases infarct size following focal cerebral ischemia in rats

Basic fibroblast growth factor is a polypeptide with potent multipotential trophic effects on central nervous system cells, including neurons, glia, and endothelial cells. In particular, it promotes the survival of a wide variety of brain neuron in vitro, and protects these neurons against the effec...

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Veröffentlicht in:	Annals of neurology 1994-04, Vol.35 (4), p.451-457
Hauptverfasser:	Koketsu, Naoki, Berlove, David J., Moskowitz, Michael A., Kowall, Neil W., Caday, Cornelio G., Finklestein, Seth P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Biological and medical sciences Cerebral Infarction - etiology Cerebral Infarction - pathology Cerebral Infarction - prevention & control Fibroblast Growth Factor 2 - administration & dosage Fibroblast Growth Factor 2 - therapeutic use Injections, Intraventricular Ischemic Attack, Transient - complications Ischemic Attack, Transient - pathology Male Medical sciences Neuropharmacology Neuroprotective agent Pharmacology. Drug treatments Rats
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