The immune cytokine granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) is an effective treatment for both Alzheimer’s disease and the viral diseases caused by West Nile Virus and SARS‐CoV‐2 infection, indicating that inflammation and viral infection may be partners and therapeutic co‐targets in many brain disorders

Background GM‐CSF has been considered a potential therapeutic target in many disorders associated with inflammation because it is upregulated and upregulates other inflammatory molecules such as IL‐1, IL‐6, and TNF‐a. However, its ability to increase the number and activation of phagocytic cells in...

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Veröffentlicht in:Alzheimer's & dementia 2023-12, Vol.19 (S21), p.n/a
Hauptverfasser: Potter, Huntington, Boyd, Timothy D., Woodcock, Jonathan H, Sillau, Stefan H, Ahmed, Md. Mahiuddin, Wang, Athena Ching‐Jung, Chial, Heidi J, Coughlan, Christina M, Kendall, Lon V., Bosco‐Lauth, Angela, Markham, Neil, Stonedahl, Sarah, Fong, Derek, Clarke, Penny, Tyler, Kenneth L.
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Sprache:eng
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