Fosgonimeton, a Small‐Molecule Positive Modulator of the HGF/MET System, Attenuates Amyloid‐β – Mediated Toxicity in Primary Neuron Culture

Background Positive modulation of the hepatocyte growth factor (HGF)/MET system may represent a promising therapeutic strategy for Alzheimer’s disease (AD). Downstream effectors of HGF/MET, such as AKT or ERK, have been shown to activate pro‐survival signaling cascades that counteract pathological c...

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Veröffentlicht in:Alzheimer's & dementia 2023-12, Vol.19 (S13), p.n/a
Hauptverfasser: Reda, Sherif, Wu, Wei, Helton, Leah, Taylor, Robert W, Johnston, Jewel L, Church, Kevin J.
Format: Artikel
Sprache:eng
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