Deciphering the Genomic Regulatory Architecture of iPSC Derived Oligodendrocytes from Diverse Ancestries for Alzheimer’s Disease Studies

Background The effect of variants associated with Alzheimer’s disease (AD) can be influenced by ancestry, which determines the genomic regulatory architecture (GRA). A global understanding of GRA in the context of AD is imperative to interpret the variability associated with AD risk genes across pop...

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Veröffentlicht in:Alzheimer's & dementia 2023-12, Vol.19 (S12), p.n/a
Hauptverfasser: Ramirez, Aura M, Shepherd, Jihanne J, Coombs, Lauren, Simon, Shaina A., Moura, Sofia, Rajabli, Farid, DeRosa, Brooke A., Muniz, Maria, Whitehead, Patrice, Adams, Larry D., Mena, Pedro R., Illanes‐Manrique, Maryenela Z, Starks, Takiyah D., Tejada, Sergio J., Byrd, Goldie S., Cornejo‐Olivas, Mario, Feliciano‐Astacio, Briseida E., Rissman, Robert A, Wang, Liyong, Xu, Wanying, Jin, Fulai, Griswold, Anthony J., Young, Juan I., Dykxhoorn, Derek M., Vance, Jeffery M.
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Sprache:eng
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