Deletion of miR‐155 in microglia enhances their response to neurodegeneration and mitigates cognitive impairment in a mouse model of Alzheimer’s disease

Background Microglia, the resident brain immune cells, play a critical role in brain homeostasis and disease progression. In neurodegenerative conditions, microglia acquire the neurodegenerative phenotype (MGnD), whose function is poorly understood. MicroRNA‐155 (miR‐155), enriched in immune cells,...

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Veröffentlicht in:	Alzheimer's & dementia 2023-12, Vol.19 (S12), p.n/a
Hauptverfasser:	Yin, Zhuoran, Herron, Shawn, Silveira, Sebastian, Kleemann, Kilian, Gauthier, Christian, Mallah, Dania, Cheng, Caterina, Margeta, Milica, Pitts, Kristen, Barry, Jen‐Li, Subramanian, Ayshwarya, Shorey, Hannah, Brandao, Wesley N, Durao, Ana, Delpech, Jean Christophe, Madore, Charlotte, Jedrychowski, Mark P, Ajay, Amrendra K., Gopal, Murugaiyan, Hersh, Samuel Walter, Ikezu, Seiko, Ikezu, Tsuneya, Butovsky, Oleg
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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