Cholesterol and matrisome pathways dysregulated by APOE4 in human glia

Background The association of Apolipoprotein E (APOE) ɛ4 risk with Alzheimer’s disease (AD) is well‐established. However, the impact of APOE ɛ4 on human brain cell function remains unclear. We hypothesized that human APOE ε4/ε4 (APOE 44) genotype contributes to disease risk through cell autonomous a...

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Veröffentlicht in:	Alzheimer's & dementia 2023-12, Vol.19 (S13), p.n/a
Hauptverfasser:	TCW, Julia, Qian, Lu, Rosa, Juao‐Guilherme S, Tuck, Tony, Scrivo, Aurora, Cuervo, Ana Maria
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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