Correction of mTORC1‐mediated brain protein synthesis rescues memory in mouse models of Alzheimer’s disease

Background Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by synapse failure and cognitive decline. Brain mRNA translation is central to synaptic plasticity and cognition, and converging evidence indicates it is impaired in AD. The mammalian target of rapamycin complex 1 (mTO...

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Veröffentlicht in:	Alzheimer's & dementia 2023-12, Vol.19 (S13), p.n/a
Hauptverfasser:	Cozachenco, Danielle, Ribeiro, Felipe C., Argyrousi, Elentina K., Staniszewski, Agnieszka, De Felice, Fernanda G., Lourenco, Mychael V., Arancio, Ottavio, Aguilar‐Valles, Argel, Sonenberg, Nahum, Ferreira, Sergio T.
Format:	Artikel
Sprache:	eng
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