Capturing DNA methylation heterogeneity and examining its relationship to somatic mutations in Alzheimer’s disease

Background One of the barriers to the identification of molecular targets in Alzheimer’s disease (AD) is its biological heterogeneity. However, computational approaches used to quantify heterogeneity in cohorts can be improved to produce more nuanced output. We develop novel and refine existing stat...

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Veröffentlicht in:Alzheimer's & dementia 2022-12, Vol.18 (S4), p.n/a
Hauptverfasser: Markov, Yaroslav, Thrush, Kyra, Higgins‐Chen, Albert, Morgan, Levine
Format: Artikel
Sprache:eng
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