Dissecting cell‐subtype specific regulatory variants and their target genes underpinning the pathogenesis of late onset Alzheimer’s disease

Background The genetic architecture of late‐onset Alzheimer’s disease (LOAD) is yet to be fully explored. While GWAS discovered numerous LOAD‐associated loci, the causal variants and their target genes remain largely unknown. We aim to advance our understanding of the genetic architecture of LOAD by...

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Veröffentlicht in:Alzheimer's & dementia 2022-12, Vol.18 (S3), p.n/a
Hauptverfasser: Gamache, Julia, Gingerich, Daniel, Garrett, Melanie E, Barrera, Julio, Ashley‐Koch, Allison, Crawford, Gregory, Chiba‐Falek, Ornit
Format: Artikel
Sprache:eng
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