Identification of ABCA7 SNP‐by‐CpG interactions associated with cognition in older African Americans

Background The ABCA7 gene confers the largest genetic risk for Alzheimer’s Disease (AD) in African Americans (AA) after APOE ε4. However, the relationship between ABCA7 and cognitive function has not been thoroughly examined in AA without dementia. We investigated the effect of genetic variants and...

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Veröffentlicht in:Alzheimer's & dementia 2022-12, Vol.18 (S3), p.n/a
Hauptverfasser: Chaar, Dima Leila, Nguyen, Kim, Wang, Yi Zhe, Ratliff, Scott, Mosley, Thomas H, Kardia, Sharon L R, Smith, Jennifer A, Zhao, Wei
Format: Artikel
Sprache:eng
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