Digital Pathology Investigation of SERPINA5‐Tau Protein Interaction in Alzheimer’s Disease and Primary Tauopathies

Background We recently discovered a novel tau binding partner, SERPINA5, to be upregulated in Alzheimer’s disease (AD) and co‐localize with corticolimbic tau distribution. As tau pathology is also observed in primary tauopathies, we hypothesized that SERPINA5 burden would mirror tau burden in these...

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Veröffentlicht in:Alzheimer's & dementia 2022-12, Vol.18 (S4), p.n/a
Hauptverfasser: Sirmans, Tiffany N. Hicks, Kouri, Naomi, Tamvaka, Nicole, Labuzan, Sydney A, Matchett, Billie J, Lincoln, Sarah J., Hinkle, Kelly M, Moloney, Christina M., Peng, Zhongwei, Carter, Rickey E, Ross, Owen A., Ertekin‐Taner, Nilufer, Duara, Ranjan, Graff‐Radford, Neill R., Dickson, Dennis W., Murray, Melissa E.
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Sprache:eng
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