Neurological and cognitive impairment in COVID‐19: clinical characterization andepidemiological
Background COVID‐19 neurological manifestations were demonstrated during the pandemic, including cognitive impairment. Objectives: To determine the prevalence of cognitive and behavioral complaints (such as dementia, MCI or SCD) in a outpatient sample with recent SARS‐COV2 infection. Specific: Evalu...
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| Veröffentlicht in: | Alzheimer's & dementia 2023-06, Vol.19 (S4), p.n/a |
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| creator | Júnior, José Wagner Leonel Tavares Neto, Pedro Braga Neto, Manoel Alves Sobreira MONTENEGRO, RAQUEL CARVALHO MOREIRA, CAROLINE DE FÁTIMA AQUINO de Oliveira, Lais Lacerda Brasil da Silva, Jean Breno Silveira Gomes, Carmem Meyve Pereira Gaspar, Safira de Brito Cunha, Letícia Chaves Vieira Sousa, Artur Victor Menezes Feitosa, Werbety Lucas Queiroz Oliveira, Danilo Nunes |
| description | Background
COVID‐19 neurological manifestations were demonstrated during the pandemic, including cognitive impairment. Objectives: To determine the prevalence of cognitive and behavioral complaints (such as dementia, MCI or SCD) in a outpatient sample with recent SARS‐COV2 infection. Specific: Evaluate the association of cognitive impairment with the presence of the polymorphism found in the APOE gene and with respiratory disease
Method
Observational, longitudinal, prospective clinical study. Inclusion criteria: patients with confirmed Covid‐19. Patients are evaluated in an outpatient clinic. They are evaluated through a standardized attendance record, with somatic and cognitive neurological assessment. Cognitive assessment involves the application of cognitive (ACER, MMSE and CDR), functional (Pfeffer) and psychiatric (GDS or Beck) screening instruments, in addition to subsequent extensive neuropsychological assessment. In addition, APOE polymorphism is analysed.
Results
To date, 200 patients were evaluated. The average age is 46.5 years, with 65.4% female, 79.16% with 8 or more years of schooling, in addition to 57.5% of the sample with cognitive complaints.
Conclusions
The results so far in our study demonstrate that cognitive complaints are frequent in patients even in the chronic phase of the disease. |
| doi_str_mv | 10.1002/alz.059664 |
| format | Article |
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COVID‐19 neurological manifestations were demonstrated during the pandemic, including cognitive impairment. Objectives: To determine the prevalence of cognitive and behavioral complaints (such as dementia, MCI or SCD) in a outpatient sample with recent SARS‐COV2 infection. Specific: Evaluate the association of cognitive impairment with the presence of the polymorphism found in the APOE gene and with respiratory disease
Method
Observational, longitudinal, prospective clinical study. Inclusion criteria: patients with confirmed Covid‐19. Patients are evaluated in an outpatient clinic. They are evaluated through a standardized attendance record, with somatic and cognitive neurological assessment. Cognitive assessment involves the application of cognitive (ACER, MMSE and CDR), functional (Pfeffer) and psychiatric (GDS or Beck) screening instruments, in addition to subsequent extensive neuropsychological assessment. In addition, APOE polymorphism is analysed.
Results
To date, 200 patients were evaluated. The average age is 46.5 years, with 65.4% female, 79.16% with 8 or more years of schooling, in addition to 57.5% of the sample with cognitive complaints.
Conclusions
The results so far in our study demonstrate that cognitive complaints are frequent in patients even in the chronic phase of the disease.</description><identifier>ISSN: 1552-5260</identifier><identifier>EISSN: 1552-5279</identifier><identifier>DOI: 10.1002/alz.059664</identifier><language>eng</language><ispartof>Alzheimer's & dementia, 2023-06, Vol.19 (S4), p.n/a</ispartof><rights>2023 the Alzheimer's Association.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Falz.059664$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Falz.059664$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids></links><search><creatorcontrib>Júnior, José Wagner Leonel Tavares</creatorcontrib><creatorcontrib>Neto, Pedro Braga</creatorcontrib><creatorcontrib>Neto, Manoel Alves Sobreira</creatorcontrib><creatorcontrib>MONTENEGRO, RAQUEL CARVALHO</creatorcontrib><creatorcontrib>MOREIRA, CAROLINE DE FÁTIMA AQUINO</creatorcontrib><creatorcontrib>de Oliveira, Lais Lacerda Brasil</creatorcontrib><creatorcontrib>da Silva, Jean Breno Silveira</creatorcontrib><creatorcontrib>Gomes, Carmem Meyve Pereira</creatorcontrib><creatorcontrib>Gaspar, Safira de Brito</creatorcontrib><creatorcontrib>Cunha, Letícia Chaves Vieira</creatorcontrib><creatorcontrib>Sousa, Artur Victor Menezes</creatorcontrib><creatorcontrib>Feitosa, Werbety Lucas Queiroz</creatorcontrib><creatorcontrib>Oliveira, Danilo Nunes</creatorcontrib><title>Neurological and cognitive impairment in COVID‐19: clinical characterization andepidemiological</title><title>Alzheimer's & dementia</title><description>Background
COVID‐19 neurological manifestations were demonstrated during the pandemic, including cognitive impairment. Objectives: To determine the prevalence of cognitive and behavioral complaints (such as dementia, MCI or SCD) in a outpatient sample with recent SARS‐COV2 infection. Specific: Evaluate the association of cognitive impairment with the presence of the polymorphism found in the APOE gene and with respiratory disease
Method
Observational, longitudinal, prospective clinical study. Inclusion criteria: patients with confirmed Covid‐19. Patients are evaluated in an outpatient clinic. They are evaluated through a standardized attendance record, with somatic and cognitive neurological assessment. Cognitive assessment involves the application of cognitive (ACER, MMSE and CDR), functional (Pfeffer) and psychiatric (GDS or Beck) screening instruments, in addition to subsequent extensive neuropsychological assessment. In addition, APOE polymorphism is analysed.
Results
To date, 200 patients were evaluated. The average age is 46.5 years, with 65.4% female, 79.16% with 8 or more years of schooling, in addition to 57.5% of the sample with cognitive complaints.
Conclusions
The results so far in our study demonstrate that cognitive complaints are frequent in patients even in the chronic phase of the disease.</description><issn>1552-5260</issn><issn>1552-5279</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp9kD1Ow0AQRlcIJEKg4QSukRxmbO_apovCX6SINEBBY43Xu2GQ_7Q2oKTiCJyRk5CQQEk1U7zvFU-IU4QRAgTnVK5GIFOloj0xQCkDXwZxuv_3KzgUR133AhBBgnIg6M68uqZsFqyp9KguPN0sau75zXhctcSuMnXvce1N5o_Ty6-PT0wvPF1y_TPQz-RI98bxinpu6o3BtFyYin-lx-LAUtmZk90diofrq_vJrT-b30wn45mvEcPIJ5lHeWwiDGyeECVSKR3HYBWBsdIaAK0KhCKRqOMw1XkOkEhLNglRU5qGQ3G29WrXdJ0zNmsdV-SWGUK2iZOt42TbOGsYt_A7l2b5D5mNZ0-7zTd_NWl8</recordid><startdate>202306</startdate><enddate>202306</enddate><creator>Júnior, José Wagner Leonel Tavares</creator><creator>Neto, Pedro Braga</creator><creator>Neto, Manoel Alves Sobreira</creator><creator>MONTENEGRO, RAQUEL CARVALHO</creator><creator>MOREIRA, CAROLINE DE FÁTIMA AQUINO</creator><creator>de Oliveira, Lais Lacerda Brasil</creator><creator>da Silva, Jean Breno Silveira</creator><creator>Gomes, Carmem Meyve Pereira</creator><creator>Gaspar, Safira de Brito</creator><creator>Cunha, Letícia Chaves Vieira</creator><creator>Sousa, Artur Victor Menezes</creator><creator>Feitosa, Werbety Lucas Queiroz</creator><creator>Oliveira, Danilo Nunes</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>202306</creationdate><title>Neurological and cognitive impairment in COVID‐19: clinical characterization andepidemiological</title><author>Júnior, José Wagner Leonel Tavares ; Neto, Pedro Braga ; Neto, Manoel Alves Sobreira ; MONTENEGRO, RAQUEL CARVALHO ; MOREIRA, CAROLINE DE FÁTIMA AQUINO ; de Oliveira, Lais Lacerda Brasil ; da Silva, Jean Breno Silveira ; Gomes, Carmem Meyve Pereira ; Gaspar, Safira de Brito ; Cunha, Letícia Chaves Vieira ; Sousa, Artur Victor Menezes ; Feitosa, Werbety Lucas Queiroz ; Oliveira, Danilo Nunes</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1134-a5b4b7e412fb8aa8566c770f6a0ef5fe00c6d10d851c739cbb0085faf831ca993</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Júnior, José Wagner Leonel Tavares</creatorcontrib><creatorcontrib>Neto, Pedro Braga</creatorcontrib><creatorcontrib>Neto, Manoel Alves Sobreira</creatorcontrib><creatorcontrib>MONTENEGRO, RAQUEL CARVALHO</creatorcontrib><creatorcontrib>MOREIRA, CAROLINE DE FÁTIMA AQUINO</creatorcontrib><creatorcontrib>de Oliveira, Lais Lacerda Brasil</creatorcontrib><creatorcontrib>da Silva, Jean Breno Silveira</creatorcontrib><creatorcontrib>Gomes, Carmem Meyve Pereira</creatorcontrib><creatorcontrib>Gaspar, Safira de Brito</creatorcontrib><creatorcontrib>Cunha, Letícia Chaves Vieira</creatorcontrib><creatorcontrib>Sousa, Artur Victor Menezes</creatorcontrib><creatorcontrib>Feitosa, Werbety Lucas Queiroz</creatorcontrib><creatorcontrib>Oliveira, Danilo Nunes</creatorcontrib><collection>CrossRef</collection><jtitle>Alzheimer's & dementia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Júnior, José Wagner Leonel Tavares</au><au>Neto, Pedro Braga</au><au>Neto, Manoel Alves Sobreira</au><au>MONTENEGRO, RAQUEL CARVALHO</au><au>MOREIRA, CAROLINE DE FÁTIMA AQUINO</au><au>de Oliveira, Lais Lacerda Brasil</au><au>da Silva, Jean Breno Silveira</au><au>Gomes, Carmem Meyve Pereira</au><au>Gaspar, Safira de Brito</au><au>Cunha, Letícia Chaves Vieira</au><au>Sousa, Artur Victor Menezes</au><au>Feitosa, Werbety Lucas Queiroz</au><au>Oliveira, Danilo Nunes</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neurological and cognitive impairment in COVID‐19: clinical characterization andepidemiological</atitle><jtitle>Alzheimer's & dementia</jtitle><date>2023-06</date><risdate>2023</risdate><volume>19</volume><issue>S4</issue><epage>n/a</epage><issn>1552-5260</issn><eissn>1552-5279</eissn><abstract>Background
COVID‐19 neurological manifestations were demonstrated during the pandemic, including cognitive impairment. Objectives: To determine the prevalence of cognitive and behavioral complaints (such as dementia, MCI or SCD) in a outpatient sample with recent SARS‐COV2 infection. Specific: Evaluate the association of cognitive impairment with the presence of the polymorphism found in the APOE gene and with respiratory disease
Method
Observational, longitudinal, prospective clinical study. Inclusion criteria: patients with confirmed Covid‐19. Patients are evaluated in an outpatient clinic. They are evaluated through a standardized attendance record, with somatic and cognitive neurological assessment. Cognitive assessment involves the application of cognitive (ACER, MMSE and CDR), functional (Pfeffer) and psychiatric (GDS or Beck) screening instruments, in addition to subsequent extensive neuropsychological assessment. In addition, APOE polymorphism is analysed.
Results
To date, 200 patients were evaluated. The average age is 46.5 years, with 65.4% female, 79.16% with 8 or more years of schooling, in addition to 57.5% of the sample with cognitive complaints.
Conclusions
The results so far in our study demonstrate that cognitive complaints are frequent in patients even in the chronic phase of the disease.</abstract><doi>10.1002/alz.059664</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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| title | Neurological and cognitive impairment in COVID‐19: clinical characterization andepidemiological |
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