Prevalence of dementia in adult patients with trisomy 21

Neuropathological lesions characteristic of Alzheimers' disease (AD) are found in all the brains of patients with trisomy 21 who die after age 40 years. However, clinical signs of AD are much less frequent in these patients. Previous studies indicate prevalence figures ranging from 15% to 51% o...

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Veröffentlicht in:	American journal of medical genetics 1990, Vol.37 (S7), p.306-308
Hauptverfasser:	Franceschi, Massimo, Comola, Mauro, Piattoni, Franca, Gualandri, Walter, Canal, Nicola
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult aging Alzheimers' disease Dementia - complications Dementia - epidemiology Down Syndrome - complications Female Humans Male Middle Aged neuropathological lesions Prevalence
Online-Zugang:	Volltext
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