Isolated thrombocytopenia induced by thalidomide in a patient with multiple myeloma: Case report and review of literature
Thalidomide is being increasingly used in hematology and oncology. Its use is associated with neuropathy, sedation, edema, fatigue, constipation, and deep venous thrombosis. Cytopenias are unusual, but there are case reports. However, there are no reports of isolated thrombocytopenia. We describe he...
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| Veröffentlicht in: | American journal of hematology 2007-09, Vol.82 (9), p.855-857 |
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| container_issue | 9 |
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| container_title | American journal of hematology |
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| creator | Prasad, H. Keshava Kaushal, Varsha Mehta, Paulette |
| description | Thalidomide is being increasingly used in hematology and oncology. Its use is associated with neuropathy, sedation, edema, fatigue, constipation, and deep venous thrombosis. Cytopenias are unusual, but there are case reports. However, there are no reports of isolated thrombocytopenia. We describe here a case of prolonged isolated thrombocytopenia most likely caused by thalidomide. The patient's in platelet count decreased promptly after an increase in the dose and improved after discontinuation of the drug. The relevant literature is reviewed. Am. J. Hematol., 2007. © 2007 Wiley‐Liss, Inc. |
| doi_str_mv | 10.1002/ajh.20949 |
| format | Article |
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Keshava</creatorcontrib><creatorcontrib>Kaushal, Varsha</creatorcontrib><creatorcontrib>Mehta, Paulette</creatorcontrib><title>Isolated thrombocytopenia induced by thalidomide in a patient with multiple myeloma: Case report and review of literature</title><title>American journal of hematology</title><addtitle>Am J Hematol</addtitle><description>Thalidomide is being increasingly used in hematology and oncology. Its use is associated with neuropathy, sedation, edema, fatigue, constipation, and deep venous thrombosis. Cytopenias are unusual, but there are case reports. However, there are no reports of isolated thrombocytopenia. We describe here a case of prolonged isolated thrombocytopenia most likely caused by thalidomide. The patient's in platelet count decreased promptly after an increase in the dose and improved after discontinuation of the drug. The relevant literature is reviewed. Am. J. 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Immunoglobulinopathies</subject><subject>Immunoglobulinopathies</subject><subject>Immunopathology</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Multiple Myeloma - blood</subject><subject>Multiple Myeloma - drug therapy</subject><subject>Platelet Count</subject><subject>Platelet diseases and coagulopathies</subject><subject>Thalidomide - adverse effects</subject><subject>Thrombocytopenia - chemically induced</subject><subject>Treatment Outcome</subject><issn>0361-8609</issn><issn>1096-8652</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10MFu3CAQBmBUNWq2aQ95gYhLDz1sMhjsNblFq7ZJFSmX5GyNYawlwsYCNiu_fWl3pZx64hfziRE_Y5cCrgVAdYOvu-sKtNIf2EqAbtZtU1cf2QpkI0oGfc4-p_QKIIRq4RM7F5t6A7WAFVseUvCYyfK8i2Hsg1lymGlyyN1k96YM-qXM0DsbRmepXHPkM2ZHU-YHl3d83PvsZk98XMiHEW_5FhPxSHOImeNkS3xzdOBh4N5lipj3kb6wswF9oq-n84K9_PzxvL1fPz79etjePa6NBKnXFnoSSpVfqXZoba0rog2CHUAqtVGqspaQDAHVsi20IqOGEs3Q9LJGIS_Y9-O7JoaUIg3dHN2IcekEdH_r60p93b_6ir062nnfj2Tf5amvAr6dACaDfog4GZfeXau1lLop7uboDs7T8v-N3d3v--PqPw-CiSE</recordid><startdate>200709</startdate><enddate>200709</enddate><creator>Prasad, H. 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| ispartof | American journal of hematology, 2007-09, Vol.82 (9), p.855-857 |
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| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Access via Wiley Online Library; Wiley Free Content |
| subjects | Biological and medical sciences Dose-Response Relationship, Drug Hematologic and hematopoietic diseases Humans Immunodeficiencies. Immunoglobulinopathies Immunoglobulinopathies Immunopathology Medical sciences Middle Aged Multiple Myeloma - blood Multiple Myeloma - drug therapy Platelet Count Platelet diseases and coagulopathies Thalidomide - adverse effects Thrombocytopenia - chemically induced Treatment Outcome |
| title | Isolated thrombocytopenia induced by thalidomide in a patient with multiple myeloma: Case report and review of literature |
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