N 6 -Methyladenosine Regulates Cilia Elongation in Cancer Cells by Modulating HDAC6 Expression

Primary cilia are microtubule-based organelles that function as cellular antennae to address multiple metabolic and extracellular cues. The past decade has seen significant advances in understanding the pro-tumorigenic role of N -methyladenosine (m A) modification in tumorigenesis. Nevertheless, whe...

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Veröffentlicht in:	Advanced science 2025-01, Vol.12 (2), p.e2408488
Hauptverfasser:	Rui, Yalan, Zhang, Haisheng, Yu, Kangning, Qiao, Shiyao, Gao, Chenglin, Wang, Xiansong, Yang, Weifeng, Asadikaram, Gholamreza, Li, Zigang, Zhang, Kun, Peng, Jianxin, Li, Jiexin, He, Junming, Wang, Hongsheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - analogs & derivatives Adenosine - genetics Adenosine - metabolism Animals Cell Line, Tumor Cilia - genetics Cilia - metabolism Disease Models, Animal Female Histone Deacetylase 6 - genetics Histone Deacetylase 6 - metabolism Humans Methyltransferases - genetics Methyltransferases - metabolism Mice Tubulin - genetics Tubulin - metabolism Uterine Cervical Neoplasms - genetics Uterine Cervical Neoplasms - metabolism Uterine Cervical Neoplasms - pathology
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