Discovery of Small Anti‐ACE2 Peptides to Inhibit SARS‐CoV‐2 Infectivity (Adv. Therap. 7/2021)

SARS‐CoV‐2 infects human cells by binding its spike protein to the human ACE2 receptor. Using a peptide biopanning strategy, the authors have discovered small anti‐ACE2 peptides that can effectively block the SARS‐CoV‐2/ACE2 interaction. The anti‐ACE2 peptides can be potentially used as prophylactic...

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Veröffentlicht in:Advanced therapeutics 2021-07, Vol.4 (7), p.n/a
Hauptverfasser: Adhikary, Pratik, Kandel, Sashi, Mamani, Umar‐Farouk, Mustafa, Bahaa, Hao, Siyuan, Qiu, Jianming, Fetse, John, Liu, Yanli, Ibrahim, Nurudeen Mohammed, Li, Yongren, Lin, Chien‐Yu, Omoscharka, Evanthia, Cheng, Kun
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container_issue 7
container_start_page
container_title Advanced therapeutics
container_volume 4
creator Adhikary, Pratik
Kandel, Sashi
Mamani, Umar‐Farouk
Mustafa, Bahaa
Hao, Siyuan
Qiu, Jianming
Fetse, John
Liu, Yanli
Ibrahim, Nurudeen Mohammed
Li, Yongren
Lin, Chien‐Yu
Omoscharka, Evanthia
Cheng, Kun
description SARS‐CoV‐2 infects human cells by binding its spike protein to the human ACE2 receptor. Using a peptide biopanning strategy, the authors have discovered small anti‐ACE2 peptides that can effectively block the SARS‐CoV‐2/ACE2 interaction. The anti‐ACE2 peptides can be potentially used as prophylactic or therapeutic agents for SARS‐CoV‐2 and other ACE2‐mediated viruses. This is reported by Kun Cheng and co‐workers in article number 2100087.
doi_str_mv 10.1002/adtp.202170016
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title Discovery of Small Anti‐ACE2 Peptides to Inhibit SARS‐CoV‐2 Infectivity (Adv. Therap. 7/2021)
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