A Continuous‐Flow Method for the Transformation from Amides to Nitriles Catalyzed by CeO 2 in Acetonitrile

A CeO 2 ‐catalyzed method for the transformation from amides to nitriles was developed using acetonitrile as the solvent and dehydrating reagent. The transformation proceeded via a formal “water transfer” reaction between the amides and acetonitrile. We propose that the presence of oxygen defect sit...

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Veröffentlicht in:Advanced synthesis & catalysis 2023-05, Vol.365 (10), p.1618-1622
Hauptverfasser: Kobayashi, Kwihwan, Masuda, Koichiro, Feng, Fei, Rashed, Md. Nurnobi, Sato, Kazuhiko, Koumura, Nagatoshi, Kobayashi, Shū
Format: Artikel
Sprache:eng
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