Microwave-Accelerated Coupling-Isomerization Reaction (MACIR) - A General Coupling-Isomerization Synthesis of 1,3-Diarylprop-2-en-1-ones

Microwave-Accelerated Coupling-Isomerization Reaction (MACIR) - A General Coupling-Isomerization Synthesis of 1,3-Diarylprop-2-en-1-ones

The microwave‐accelerated coupling‐isomerization reaction (MACIR) of (hetero)aryl halides and propargyl alcohols represents a general Pd/Cu and base‐catalyzed process for the synthesis of 3‐arylprop‐2‐en‐1‐ones in good yields.

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Bibliographische Detailangaben
Veröffentlicht in:Advanced synthesis & catalysis 2006-12, Vol.348 (18), p.2565-2570
Hauptverfasser: Schramm (née Dediu), Oana G., Müller, Thomas J. J.
Format: Artikel
Sprache:eng
Schlagworte:
alkynes
copper
cross-coupling
isomerization
palladium
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Beschreibung
Zusammenfassung:The microwave‐accelerated coupling‐isomerization reaction (MACIR) of (hetero)aryl halides and propargyl alcohols represents a general Pd/Cu and base‐catalyzed process for the synthesis of 3‐arylprop‐2‐en‐1‐ones in good yields.
ISSN:1615-4150
1615-4169
DOI:10.1002/adsc.200600280