DNA‐Based Single Molecule Force Sensor For Characterization of α 5 β 1 Integrin Tension Required for Invadopodia Formation and Maturation in Cancer Cells

Invadopodia are involved in cancer invasion by generating mechanical forces and secreting proteolytic enzymes. It is hypothesized that physical forces applied to integrin, especially α 5 β 1 integrin, are strongly associated with the generation of invadopodial forces and protrusive activity of invad...

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Veröffentlicht in:Advanced functional materials 2022-07, Vol.32 (28)
Hauptverfasser: Kim, Kyung Ah, Vellampatti, Srivithya, Hwang, Sun Ha, Kim, Byoung Choul
Format: Artikel
Sprache:eng
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