Microneedle‐Based Local Delivery of CCL22 and IL‐2 Enriches T reg Homing to the Skin Allograft and Enables Temporal Monitoring of Immunotherapy Efficacy

Skin allografts only serve as temporary dressing for patients suffering major burns due to their high immunogenicity and rejection by the immune system, requiring systemic immunosuppressive therapies that lead to deleterious side effects. Microneedle arrays composed of hyaluronic acid (HA) and place...

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Veröffentlicht in:Advanced functional materials 2021-10, Vol.31 (44)
Hauptverfasser: Puigmal, Núria, Dosta, Pere, Solhjou, Zhabiz, Yatim, Karim, Ramírez, Cynthia, Choi, John Y., Alhaddad, Juliano B., Cosme, Ana Paula, Azzi, Jamil, Artzi, Natalie
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Sprache:eng
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