Experimental Autoimmune Myasthenia Gravis in the Mouse

Myasthenia gravis (MG) is a T cell–dependent antibody‐mediated autoimmune neuromuscular disease. Antibodies to the nicotinic acetylcholine receptor (AChR) destroy the AChR, thus leading to defective neuromuscular transmission of electrical impulse and to muscle weakness. This unit is a practical gui...

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Veröffentlicht in:	Current Protocols in Immunology 2011-11, Vol.95 (1), p.15.23.1-15.23.26
Hauptverfasser:	Wu, Bo, Goluszko, Elzbieta, Huda, Ruksana, Tüzün, Erdem, Christadoss, Premkumar
Format:	Artikel
Sprache:	eng
Schlagworte:	acetylcholine receptor Animals Electric Organ - immunology Electromyography experimental autoimmune myasthenia gravis Immunoglobulin G - immunology Mice Mice, Inbred C57BL Muscle, Skeletal - immunology myasthenia gravis Myasthenia Gravis, Autoimmune, Experimental - immunology neuromuscular junction Neuromuscular Junction - immunology Receptors, Nicotinic - immunology Receptors, Nicotinic - isolation & purification Torpedo - immunology
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