Topical Chemotherapy in Cutaneous T-cell Lymphoma: Positive Results of a Randomized, Controlled, Multicenter Trial Testing the Efficacy and Safety of a Novel Mechlorethamine, 0.02%, Gel in Mycosis Fungoides

OBJECTIVE To evaluate the efficacy and safety of a novel mechlorethamine hydrochloride, 0.02%, gel in mycosis fungoides. DESIGN Randomized, controlled, observer-blinded, multicenter trial comparing mechlorethamine, 0.02%, gel with mechlorethamine, 0.02%, compounded ointment. Mechlorethamine was appl...

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Veröffentlicht in:	Archives of dermatology (1960) 2013-01, Vol.149 (1), p.1-8
Hauptverfasser:	Lessin, Stuart R, Duvic, Madeleine, Guitart, Joan, Pandya, Amit G, Strober, Bruce E, Olsen, Elise A, Hull, Christopher M, Knobler, Elizabeth H, Rook, Alain H, Kim, Ellen J, Naylor, Mark F, Adelson, David M, Kimball, Alexa B, Wood, Gary S, Sundram, Uma, Wu, Hong, Kim, Youn H
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Adolescent Adult Aged Aged, 80 and over Antineoplastic Agents, Alkylating - administration & dosage Antineoplastic Agents, Alkylating - adverse effects Antineoplastic Agents, Alkylating - therapeutic use Female Gels Humans Male Mechlorethamine - administration & dosage Mechlorethamine - adverse effects Mechlorethamine - therapeutic use Middle Aged Mycosis Fungoides - drug therapy Mycosis Fungoides - pathology Neoplasm Staging Ointments Severity of Illness Index Single-Blind Method Skin Neoplasms - drug therapy Skin Neoplasms - pathology Time Factors Treatment Outcome Young Adult
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