Optimization of receptor occupancy assays in mass cytometry: Standardization across channels with QSC beads

Receptor occupancy, the ratio between amount of drug bound and amount of total receptor on single cells, is a biomarker for treatment response to therapeutic monoclonal antibodies. Receptor occupancy is traditionally measured by flow cytometry. However, spectral overlap in flow cytometry limits the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	Bringeland, Gerd Haga, Bader, Lucius, Blaser, Nello, Budzinski, Lisa, Schulz, Axel R, Mei, Henrik E, Myhr, Kjell-Morten, Vedeler, Christian A, Gavasso, Sonia
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!