Burden of diarrhea in the Eastern Mediterranean Region, 1990-2015: Findings from the Global Burden of Disease 2015 study

Objectives: Diarrheal diseases (DD) are an important cause of disease burden, especially in children in low-income settings. DD can also impact children’s potential livelihood through growth faltering, cognitive impairment, and other sequelae. Methods: As part of the Global Burden of Disease study,...

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Hauptverfasser: Mokdad, Ali H, Khalil, Ibrahim, El Bcheraoui, Charbel, Moradi-Lakeh, Maziar, Afshin, Ashkan, Kassebaum, Nicholas J, Chew, Adrienne, Daoud, Farah, Foreman, Kyle J, Godwin, William W, Kutz, Michael, Troeger, Christopher, Wang, Haidong, Abu-Raddad, Laith J, Ahmad Kiadaliri, Aliasghar, Ahmadi, Alireza, Alam, Khurshid, Alizadeh-Navaei, Reza, Al-Raddadi, Rajaa, Altirkawi, Khalid A, Alvis-Guzman, Nelson, Anber, Nahla, Anwari, Palwasha, Mehari Atey, Tesfay, Avokpaho, Euripide Frinel G. Arthur, Bazargan-Hejazi, Shahrzad, Bedi, Neeraj, Bensenor, Isabela M, Berhane, Adugnaw, Shunu Beyene, Addisu, Bhutta, Zulfiqar A, Colin Buckle, Geoffrey, Butt, Zahid A, Danawi, Hadi, Deribew, Amare, Djalalinia, Shirin, Dubey, Manisha, Endries, Aman Yesuf, Fereshtehnejad, Seyed-Mohammad, Fischer, Florian, Tewelde Gebrehiwot, Tsegaye, Ribhi Hamadeh, Randah, Hamidi, Samer, Husseini, Abdullatif, James, Spencer Lewis, Jonas, Jost B, Kasaeian, Amir, Saleh Khader, Yousef, Ahmad Khan, Ejaz, Khan, Gulfaraz, Kopec, Jacek A, Koyanagi, Ai, Abdul Latif, Asma, Abd El Razek, Hassan Magdy, Abd El Razek, Mohammed Magdy, Majdzadeh, Reza, Majeed, Azeem, Memish, Ziad A, Tadese Mengistu, Desalegn, Mohammed, Shafiu, Murthy, Srinivas, Pourmalek, Farshad, Qorbani, Mostafa, Radfar, Amir, Rahimi-Movaghar, Vafa, Kumar Rai, Rajesh, Ram, Usha, Laith Rawaf, David, Rawaf, Salman, Rezaei, Satar, Roshandel, Gholamreza, Safdarian, Mahdi, Ali Sahraian, Mohammad, Salamati, Payman, Ramon Sanabria, Juan, Ali Shaikh, Masood, Shigematsu, Mika, Sobaih, Badr H.A, Sykes, Bryan L, Tehrani-Banihashemi, Arash, Temsah, Mohamad-Hani, Sulieman Terkawi, Abdullah, Tiruye, Tenaw Yimer, Topor-Madry, Roman, Vollset, Stein Emil, Wakayo, Tolassa, Shey Wiysonge, Charles, Workicho, Abdulhalik, Yaghoubi, Mohsen, Yaseri, Mehdi, Yenesew, Muluken, Yonemoto, Naohiro, Younis, Mustafa Z, El Sayed Zaki, Maysaa, Zodpey, Sanjay, Jumaan, Aisha O, Vos, Theo, Hay, Simon I, Naghavi, Mohsen, Murray, Christopher J.L
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creator Mokdad, Ali H
Khalil, Ibrahim
El Bcheraoui, Charbel
Moradi-Lakeh, Maziar
Afshin, Ashkan
Kassebaum, Nicholas J
Chew, Adrienne
Daoud, Farah
Foreman, Kyle J
Godwin, William W
Kutz, Michael
Troeger, Christopher
Wang, Haidong
Abu-Raddad, Laith J
Ahmad Kiadaliri, Aliasghar
Ahmadi, Alireza
Alam, Khurshid
Alizadeh-Navaei, Reza
Al-Raddadi, Rajaa
Altirkawi, Khalid A
Alvis-Guzman, Nelson
Anber, Nahla
Anwari, Palwasha
Mehari Atey, Tesfay
Avokpaho, Euripide Frinel G. Arthur
Bazargan-Hejazi, Shahrzad
Bedi, Neeraj
Bensenor, Isabela M
Berhane, Adugnaw
Shunu Beyene, Addisu
Bhutta, Zulfiqar A
Colin Buckle, Geoffrey
Butt, Zahid A
Danawi, Hadi
Deribew, Amare
Djalalinia, Shirin
Dubey, Manisha
Endries, Aman Yesuf
Fereshtehnejad, Seyed-Mohammad
Fischer, Florian
Tewelde Gebrehiwot, Tsegaye
Ribhi Hamadeh, Randah
Hamidi, Samer
Husseini, Abdullatif
James, Spencer Lewis
Jonas, Jost B
Kasaeian, Amir
Saleh Khader, Yousef
Ahmad Khan, Ejaz
Khan, Gulfaraz
Kopec, Jacek A
Koyanagi, Ai
Abdul Latif, Asma
Abd El Razek, Hassan Magdy
Abd El Razek, Mohammed Magdy
Majdzadeh, Reza
Majeed, Azeem
Memish, Ziad A
Tadese Mengistu, Desalegn
Mohammed, Shafiu
Murthy, Srinivas
Pourmalek, Farshad
Qorbani, Mostafa
Radfar, Amir
Rahimi-Movaghar, Vafa
Kumar Rai, Rajesh
Ram, Usha
Laith Rawaf, David
Rawaf, Salman
Rezaei, Satar
Roshandel, Gholamreza
Safdarian, Mahdi
Ali Sahraian, Mohammad
Salamati, Payman
Ramon Sanabria, Juan
Ali Shaikh, Masood
Shigematsu, Mika
Sobaih, Badr H.A
Sykes, Bryan L
Tehrani-Banihashemi, Arash
Temsah, Mohamad-Hani
Sulieman Terkawi, Abdullah
Tiruye, Tenaw Yimer
Topor-Madry, Roman
Vollset, Stein Emil
Wakayo, Tolassa
Shey Wiysonge, Charles
Workicho, Abdulhalik
Yaghoubi, Mohsen
Yaseri, Mehdi
Yenesew, Muluken
Yonemoto, Naohiro
Younis, Mustafa Z
El Sayed Zaki, Maysaa
Zodpey, Sanjay
Jumaan, Aisha O
Vos, Theo
Hay, Simon I
Naghavi, Mohsen
Murray, Christopher J.L
description Objectives: Diarrheal diseases (DD) are an important cause of disease burden, especially in children in low-income settings. DD can also impact children’s potential livelihood through growth faltering, cognitive impairment, and other sequelae. Methods: As part of the Global Burden of Disease study, we estimated DD burden, and the burden attributable to specific risk factors and etiologies, in the Eastern Mediterranean Region (EMR) between 1990 and 2015. We calculated disability-adjusted life-years (DALYs)—the sum of years of life lost and years lived with disability—for both sexes and all ages. Results: We estimate that over 103,692 diarrhea deaths occurred in the EMR in 2015 (95% uncertainty interval: 87,018–124,692), and the mortality rate was 16.0 deaths per 100,000 persons (95% UI: 13.4–19.2). The majority of these deaths occurred in children under 5 (63.3%) (65,670 deaths, 95% UI: 53,640–79,486). DALYs per 100,000 ranged from 304 (95% UI 228–400) in Kuwait to 38,900 (95% UI 25,900–54,300) in Somalia. Conclusions: Our findings will guide evidence-based health policy decisions for interventions to achieve the ultimate goal of reducing the DD burden.
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fullrecord <record><control><sourceid>cristin_3HK</sourceid><recordid>TN_cdi_cristin_nora_1956_19743</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1956_19743</sourcerecordid><originalsourceid>FETCH-cristin_nora_1956_197433</originalsourceid><addsrcrecordid>eNqFjLEOgkAQRGksjPoLZj9AEhDRYKmCNjbGnizeApvgXrJ3JPr3ojGxtJmZ4r0ZB49dr4YEbA2GUbUlBBbwLUGOzpMKnMnwMBSFUOBCDVtZQJxlUbiM4nQLBYthaRzUau8f9djZCjv4fR_YETqCtwDO9-Y5DUY1do5m354E8yK_7k_hTdl5llKsYhln6XqIzSpJ_gIv9BVAqQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Burden of diarrhea in the Eastern Mediterranean Region, 1990-2015: Findings from the Global Burden of Disease 2015 study</title><source>NORA - Norwegian Open Research Archives</source><creator>Mokdad, Ali H ; Khalil, Ibrahim ; El Bcheraoui, Charbel ; Moradi-Lakeh, Maziar ; Afshin, Ashkan ; Kassebaum, Nicholas J ; Chew, Adrienne ; Daoud, Farah ; Foreman, Kyle J ; Godwin, William W ; Kutz, Michael ; Troeger, Christopher ; Wang, Haidong ; Abu-Raddad, Laith J ; Ahmad Kiadaliri, Aliasghar ; Ahmadi, Alireza ; Alam, Khurshid ; Alizadeh-Navaei, Reza ; Al-Raddadi, Rajaa ; Altirkawi, Khalid A ; Alvis-Guzman, Nelson ; Anber, Nahla ; Anwari, Palwasha ; Mehari Atey, Tesfay ; Avokpaho, Euripide Frinel G. Arthur ; Bazargan-Hejazi, Shahrzad ; Bedi, Neeraj ; Bensenor, Isabela M ; Berhane, Adugnaw ; Shunu Beyene, Addisu ; Bhutta, Zulfiqar A ; Colin Buckle, Geoffrey ; Butt, Zahid A ; Danawi, Hadi ; Deribew, Amare ; Djalalinia, Shirin ; Dubey, Manisha ; Endries, Aman Yesuf ; Fereshtehnejad, Seyed-Mohammad ; Fischer, Florian ; Tewelde Gebrehiwot, Tsegaye ; Ribhi Hamadeh, Randah ; Hamidi, Samer ; Husseini, Abdullatif ; James, Spencer Lewis ; Jonas, Jost B ; Kasaeian, Amir ; Saleh Khader, Yousef ; Ahmad Khan, Ejaz ; Khan, Gulfaraz ; Kopec, Jacek A ; Koyanagi, Ai ; Abdul Latif, Asma ; Abd El Razek, Hassan Magdy ; Abd El Razek, Mohammed Magdy ; Majdzadeh, Reza ; Majeed, Azeem ; Memish, Ziad A ; Tadese Mengistu, Desalegn ; Mohammed, Shafiu ; Murthy, Srinivas ; Pourmalek, Farshad ; Qorbani, Mostafa ; Radfar, Amir ; Rahimi-Movaghar, Vafa ; Kumar Rai, Rajesh ; Ram, Usha ; Laith Rawaf, David ; Rawaf, Salman ; Rezaei, Satar ; Roshandel, Gholamreza ; Safdarian, Mahdi ; Ali Sahraian, Mohammad ; Salamati, Payman ; Ramon Sanabria, Juan ; Ali Shaikh, Masood ; Shigematsu, Mika ; Sobaih, Badr H.A ; Sykes, Bryan L ; Tehrani-Banihashemi, Arash ; Temsah, Mohamad-Hani ; Sulieman Terkawi, Abdullah ; Tiruye, Tenaw Yimer ; Topor-Madry, Roman ; Vollset, Stein Emil ; Wakayo, Tolassa ; Shey Wiysonge, Charles ; Workicho, Abdulhalik ; Yaghoubi, Mohsen ; Yaseri, Mehdi ; Yenesew, Muluken ; Yonemoto, Naohiro ; Younis, Mustafa Z ; El Sayed Zaki, Maysaa ; Zodpey, Sanjay ; Jumaan, Aisha O ; Vos, Theo ; Hay, Simon I ; Naghavi, Mohsen ; Murray, Christopher J.L</creator><creatorcontrib>Mokdad, Ali H ; Khalil, Ibrahim ; El Bcheraoui, Charbel ; Moradi-Lakeh, Maziar ; Afshin, Ashkan ; Kassebaum, Nicholas J ; Chew, Adrienne ; Daoud, Farah ; Foreman, Kyle J ; Godwin, William W ; Kutz, Michael ; Troeger, Christopher ; Wang, Haidong ; Abu-Raddad, Laith J ; Ahmad Kiadaliri, Aliasghar ; Ahmadi, Alireza ; Alam, Khurshid ; Alizadeh-Navaei, Reza ; Al-Raddadi, Rajaa ; Altirkawi, Khalid A ; Alvis-Guzman, Nelson ; Anber, Nahla ; Anwari, Palwasha ; Mehari Atey, Tesfay ; Avokpaho, Euripide Frinel G. Arthur ; Bazargan-Hejazi, Shahrzad ; Bedi, Neeraj ; Bensenor, Isabela M ; Berhane, Adugnaw ; Shunu Beyene, Addisu ; Bhutta, Zulfiqar A ; Colin Buckle, Geoffrey ; Butt, Zahid A ; Danawi, Hadi ; Deribew, Amare ; Djalalinia, Shirin ; Dubey, Manisha ; Endries, Aman Yesuf ; Fereshtehnejad, Seyed-Mohammad ; Fischer, Florian ; Tewelde Gebrehiwot, Tsegaye ; Ribhi Hamadeh, Randah ; Hamidi, Samer ; Husseini, Abdullatif ; James, Spencer Lewis ; Jonas, Jost B ; Kasaeian, Amir ; Saleh Khader, Yousef ; Ahmad Khan, Ejaz ; Khan, Gulfaraz ; Kopec, Jacek A ; Koyanagi, Ai ; Abdul Latif, Asma ; Abd El Razek, Hassan Magdy ; Abd El Razek, Mohammed Magdy ; Majdzadeh, Reza ; Majeed, Azeem ; Memish, Ziad A ; Tadese Mengistu, Desalegn ; Mohammed, Shafiu ; Murthy, Srinivas ; Pourmalek, Farshad ; Qorbani, Mostafa ; Radfar, Amir ; Rahimi-Movaghar, Vafa ; Kumar Rai, Rajesh ; Ram, Usha ; Laith Rawaf, David ; Rawaf, Salman ; Rezaei, Satar ; Roshandel, Gholamreza ; Safdarian, Mahdi ; Ali Sahraian, Mohammad ; Salamati, Payman ; Ramon Sanabria, Juan ; Ali Shaikh, Masood ; Shigematsu, Mika ; Sobaih, Badr H.A ; Sykes, Bryan L ; Tehrani-Banihashemi, Arash ; Temsah, Mohamad-Hani ; Sulieman Terkawi, Abdullah ; Tiruye, Tenaw Yimer ; Topor-Madry, Roman ; Vollset, Stein Emil ; Wakayo, Tolassa ; Shey Wiysonge, Charles ; Workicho, Abdulhalik ; Yaghoubi, Mohsen ; Yaseri, Mehdi ; Yenesew, Muluken ; Yonemoto, Naohiro ; Younis, Mustafa Z ; El Sayed Zaki, Maysaa ; Zodpey, Sanjay ; Jumaan, Aisha O ; Vos, Theo ; Hay, Simon I ; Naghavi, Mohsen ; Murray, Christopher J.L</creatorcontrib><description>Objectives: Diarrheal diseases (DD) are an important cause of disease burden, especially in children in low-income settings. DD can also impact children’s potential livelihood through growth faltering, cognitive impairment, and other sequelae. Methods: As part of the Global Burden of Disease study, we estimated DD burden, and the burden attributable to specific risk factors and etiologies, in the Eastern Mediterranean Region (EMR) between 1990 and 2015. We calculated disability-adjusted life-years (DALYs)—the sum of years of life lost and years lived with disability—for both sexes and all ages. Results: We estimate that over 103,692 diarrhea deaths occurred in the EMR in 2015 (95% uncertainty interval: 87,018–124,692), and the mortality rate was 16.0 deaths per 100,000 persons (95% UI: 13.4–19.2). The majority of these deaths occurred in children under 5 (63.3%) (65,670 deaths, 95% UI: 53,640–79,486). DALYs per 100,000 ranged from 304 (95% UI 228–400) in Kuwait to 38,900 (95% UI 25,900–54,300) in Somalia. Conclusions: Our findings will guide evidence-based health policy decisions for interventions to achieve the ultimate goal of reducing the DD burden.</description><language>eng</language><publisher>Springer International Publishing</publisher><subject>Burden of disease ; Diarrheal diseases ; Eastern Mediterranean Region</subject><creationdate>2018</creationdate><rights>info:eu-repo/semantics/openAccess</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,776,881,26544</link.rule.ids><linktorsrc>$$Uhttp://hdl.handle.net/1956/19743$$EView_record_in_NORA$$FView_record_in_$$GNORA$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Mokdad, Ali H</creatorcontrib><creatorcontrib>Khalil, Ibrahim</creatorcontrib><creatorcontrib>El Bcheraoui, Charbel</creatorcontrib><creatorcontrib>Moradi-Lakeh, Maziar</creatorcontrib><creatorcontrib>Afshin, Ashkan</creatorcontrib><creatorcontrib>Kassebaum, Nicholas J</creatorcontrib><creatorcontrib>Chew, Adrienne</creatorcontrib><creatorcontrib>Daoud, Farah</creatorcontrib><creatorcontrib>Foreman, Kyle J</creatorcontrib><creatorcontrib>Godwin, William W</creatorcontrib><creatorcontrib>Kutz, Michael</creatorcontrib><creatorcontrib>Troeger, Christopher</creatorcontrib><creatorcontrib>Wang, Haidong</creatorcontrib><creatorcontrib>Abu-Raddad, Laith J</creatorcontrib><creatorcontrib>Ahmad Kiadaliri, Aliasghar</creatorcontrib><creatorcontrib>Ahmadi, Alireza</creatorcontrib><creatorcontrib>Alam, Khurshid</creatorcontrib><creatorcontrib>Alizadeh-Navaei, Reza</creatorcontrib><creatorcontrib>Al-Raddadi, Rajaa</creatorcontrib><creatorcontrib>Altirkawi, Khalid A</creatorcontrib><creatorcontrib>Alvis-Guzman, Nelson</creatorcontrib><creatorcontrib>Anber, Nahla</creatorcontrib><creatorcontrib>Anwari, Palwasha</creatorcontrib><creatorcontrib>Mehari Atey, Tesfay</creatorcontrib><creatorcontrib>Avokpaho, Euripide Frinel G. Arthur</creatorcontrib><creatorcontrib>Bazargan-Hejazi, Shahrzad</creatorcontrib><creatorcontrib>Bedi, Neeraj</creatorcontrib><creatorcontrib>Bensenor, Isabela M</creatorcontrib><creatorcontrib>Berhane, Adugnaw</creatorcontrib><creatorcontrib>Shunu Beyene, Addisu</creatorcontrib><creatorcontrib>Bhutta, Zulfiqar A</creatorcontrib><creatorcontrib>Colin Buckle, Geoffrey</creatorcontrib><creatorcontrib>Butt, Zahid A</creatorcontrib><creatorcontrib>Danawi, Hadi</creatorcontrib><creatorcontrib>Deribew, Amare</creatorcontrib><creatorcontrib>Djalalinia, Shirin</creatorcontrib><creatorcontrib>Dubey, Manisha</creatorcontrib><creatorcontrib>Endries, Aman Yesuf</creatorcontrib><creatorcontrib>Fereshtehnejad, Seyed-Mohammad</creatorcontrib><creatorcontrib>Fischer, Florian</creatorcontrib><creatorcontrib>Tewelde Gebrehiwot, Tsegaye</creatorcontrib><creatorcontrib>Ribhi Hamadeh, Randah</creatorcontrib><creatorcontrib>Hamidi, Samer</creatorcontrib><creatorcontrib>Husseini, Abdullatif</creatorcontrib><creatorcontrib>James, Spencer Lewis</creatorcontrib><creatorcontrib>Jonas, Jost B</creatorcontrib><creatorcontrib>Kasaeian, Amir</creatorcontrib><creatorcontrib>Saleh Khader, Yousef</creatorcontrib><creatorcontrib>Ahmad Khan, Ejaz</creatorcontrib><creatorcontrib>Khan, Gulfaraz</creatorcontrib><creatorcontrib>Kopec, Jacek A</creatorcontrib><creatorcontrib>Koyanagi, Ai</creatorcontrib><creatorcontrib>Abdul Latif, Asma</creatorcontrib><creatorcontrib>Abd El Razek, Hassan Magdy</creatorcontrib><creatorcontrib>Abd El Razek, Mohammed Magdy</creatorcontrib><creatorcontrib>Majdzadeh, Reza</creatorcontrib><creatorcontrib>Majeed, Azeem</creatorcontrib><creatorcontrib>Memish, Ziad A</creatorcontrib><creatorcontrib>Tadese Mengistu, Desalegn</creatorcontrib><creatorcontrib>Mohammed, Shafiu</creatorcontrib><creatorcontrib>Murthy, Srinivas</creatorcontrib><creatorcontrib>Pourmalek, Farshad</creatorcontrib><creatorcontrib>Qorbani, Mostafa</creatorcontrib><creatorcontrib>Radfar, Amir</creatorcontrib><creatorcontrib>Rahimi-Movaghar, Vafa</creatorcontrib><creatorcontrib>Kumar Rai, Rajesh</creatorcontrib><creatorcontrib>Ram, Usha</creatorcontrib><creatorcontrib>Laith Rawaf, David</creatorcontrib><creatorcontrib>Rawaf, Salman</creatorcontrib><creatorcontrib>Rezaei, Satar</creatorcontrib><creatorcontrib>Roshandel, Gholamreza</creatorcontrib><creatorcontrib>Safdarian, Mahdi</creatorcontrib><creatorcontrib>Ali Sahraian, Mohammad</creatorcontrib><creatorcontrib>Salamati, Payman</creatorcontrib><creatorcontrib>Ramon Sanabria, Juan</creatorcontrib><creatorcontrib>Ali Shaikh, Masood</creatorcontrib><creatorcontrib>Shigematsu, Mika</creatorcontrib><creatorcontrib>Sobaih, Badr H.A</creatorcontrib><creatorcontrib>Sykes, Bryan L</creatorcontrib><creatorcontrib>Tehrani-Banihashemi, Arash</creatorcontrib><creatorcontrib>Temsah, Mohamad-Hani</creatorcontrib><creatorcontrib>Sulieman Terkawi, Abdullah</creatorcontrib><creatorcontrib>Tiruye, Tenaw Yimer</creatorcontrib><creatorcontrib>Topor-Madry, Roman</creatorcontrib><creatorcontrib>Vollset, Stein Emil</creatorcontrib><creatorcontrib>Wakayo, Tolassa</creatorcontrib><creatorcontrib>Shey Wiysonge, Charles</creatorcontrib><creatorcontrib>Workicho, Abdulhalik</creatorcontrib><creatorcontrib>Yaghoubi, Mohsen</creatorcontrib><creatorcontrib>Yaseri, Mehdi</creatorcontrib><creatorcontrib>Yenesew, Muluken</creatorcontrib><creatorcontrib>Yonemoto, Naohiro</creatorcontrib><creatorcontrib>Younis, Mustafa Z</creatorcontrib><creatorcontrib>El Sayed Zaki, Maysaa</creatorcontrib><creatorcontrib>Zodpey, Sanjay</creatorcontrib><creatorcontrib>Jumaan, Aisha O</creatorcontrib><creatorcontrib>Vos, Theo</creatorcontrib><creatorcontrib>Hay, Simon I</creatorcontrib><creatorcontrib>Naghavi, Mohsen</creatorcontrib><creatorcontrib>Murray, Christopher J.L</creatorcontrib><title>Burden of diarrhea in the Eastern Mediterranean Region, 1990-2015: Findings from the Global Burden of Disease 2015 study</title><description>Objectives: Diarrheal diseases (DD) are an important cause of disease burden, especially in children in low-income settings. DD can also impact children’s potential livelihood through growth faltering, cognitive impairment, and other sequelae. Methods: As part of the Global Burden of Disease study, we estimated DD burden, and the burden attributable to specific risk factors and etiologies, in the Eastern Mediterranean Region (EMR) between 1990 and 2015. We calculated disability-adjusted life-years (DALYs)—the sum of years of life lost and years lived with disability—for both sexes and all ages. Results: We estimate that over 103,692 diarrhea deaths occurred in the EMR in 2015 (95% uncertainty interval: 87,018–124,692), and the mortality rate was 16.0 deaths per 100,000 persons (95% UI: 13.4–19.2). The majority of these deaths occurred in children under 5 (63.3%) (65,670 deaths, 95% UI: 53,640–79,486). DALYs per 100,000 ranged from 304 (95% UI 228–400) in Kuwait to 38,900 (95% UI 25,900–54,300) in Somalia. Conclusions: Our findings will guide evidence-based health policy decisions for interventions to achieve the ultimate goal of reducing the DD burden.</description><subject>Burden of disease</subject><subject>Diarrheal diseases</subject><subject>Eastern Mediterranean Region</subject><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>3HK</sourceid><recordid>eNqFjLEOgkAQRGksjPoLZj9AEhDRYKmCNjbGnizeApvgXrJ3JPr3ojGxtJmZ4r0ZB49dr4YEbA2GUbUlBBbwLUGOzpMKnMnwMBSFUOBCDVtZQJxlUbiM4nQLBYthaRzUau8f9djZCjv4fR_YETqCtwDO9-Y5DUY1do5m354E8yK_7k_hTdl5llKsYhln6XqIzSpJ_gIv9BVAqQ</recordid><startdate>2018</startdate><enddate>2018</enddate><creator>Mokdad, Ali H</creator><creator>Khalil, Ibrahim</creator><creator>El Bcheraoui, Charbel</creator><creator>Moradi-Lakeh, Maziar</creator><creator>Afshin, Ashkan</creator><creator>Kassebaum, Nicholas J</creator><creator>Chew, Adrienne</creator><creator>Daoud, Farah</creator><creator>Foreman, Kyle J</creator><creator>Godwin, William W</creator><creator>Kutz, Michael</creator><creator>Troeger, Christopher</creator><creator>Wang, Haidong</creator><creator>Abu-Raddad, Laith J</creator><creator>Ahmad Kiadaliri, Aliasghar</creator><creator>Ahmadi, Alireza</creator><creator>Alam, Khurshid</creator><creator>Alizadeh-Navaei, Reza</creator><creator>Al-Raddadi, Rajaa</creator><creator>Altirkawi, Khalid A</creator><creator>Alvis-Guzman, Nelson</creator><creator>Anber, Nahla</creator><creator>Anwari, Palwasha</creator><creator>Mehari Atey, Tesfay</creator><creator>Avokpaho, Euripide Frinel G. Arthur</creator><creator>Bazargan-Hejazi, Shahrzad</creator><creator>Bedi, Neeraj</creator><creator>Bensenor, Isabela M</creator><creator>Berhane, Adugnaw</creator><creator>Shunu Beyene, Addisu</creator><creator>Bhutta, Zulfiqar A</creator><creator>Colin Buckle, Geoffrey</creator><creator>Butt, Zahid A</creator><creator>Danawi, Hadi</creator><creator>Deribew, Amare</creator><creator>Djalalinia, Shirin</creator><creator>Dubey, Manisha</creator><creator>Endries, Aman Yesuf</creator><creator>Fereshtehnejad, Seyed-Mohammad</creator><creator>Fischer, Florian</creator><creator>Tewelde Gebrehiwot, Tsegaye</creator><creator>Ribhi Hamadeh, Randah</creator><creator>Hamidi, Samer</creator><creator>Husseini, Abdullatif</creator><creator>James, Spencer Lewis</creator><creator>Jonas, Jost B</creator><creator>Kasaeian, Amir</creator><creator>Saleh Khader, Yousef</creator><creator>Ahmad Khan, Ejaz</creator><creator>Khan, Gulfaraz</creator><creator>Kopec, Jacek A</creator><creator>Koyanagi, Ai</creator><creator>Abdul Latif, Asma</creator><creator>Abd El Razek, Hassan Magdy</creator><creator>Abd El Razek, Mohammed Magdy</creator><creator>Majdzadeh, Reza</creator><creator>Majeed, Azeem</creator><creator>Memish, Ziad A</creator><creator>Tadese Mengistu, Desalegn</creator><creator>Mohammed, Shafiu</creator><creator>Murthy, Srinivas</creator><creator>Pourmalek, Farshad</creator><creator>Qorbani, Mostafa</creator><creator>Radfar, Amir</creator><creator>Rahimi-Movaghar, Vafa</creator><creator>Kumar Rai, Rajesh</creator><creator>Ram, Usha</creator><creator>Laith Rawaf, David</creator><creator>Rawaf, Salman</creator><creator>Rezaei, Satar</creator><creator>Roshandel, Gholamreza</creator><creator>Safdarian, Mahdi</creator><creator>Ali Sahraian, Mohammad</creator><creator>Salamati, Payman</creator><creator>Ramon Sanabria, Juan</creator><creator>Ali Shaikh, Masood</creator><creator>Shigematsu, Mika</creator><creator>Sobaih, Badr H.A</creator><creator>Sykes, Bryan L</creator><creator>Tehrani-Banihashemi, Arash</creator><creator>Temsah, Mohamad-Hani</creator><creator>Sulieman Terkawi, Abdullah</creator><creator>Tiruye, Tenaw Yimer</creator><creator>Topor-Madry, Roman</creator><creator>Vollset, Stein Emil</creator><creator>Wakayo, Tolassa</creator><creator>Shey Wiysonge, Charles</creator><creator>Workicho, Abdulhalik</creator><creator>Yaghoubi, Mohsen</creator><creator>Yaseri, Mehdi</creator><creator>Yenesew, Muluken</creator><creator>Yonemoto, Naohiro</creator><creator>Younis, Mustafa Z</creator><creator>El Sayed Zaki, Maysaa</creator><creator>Zodpey, Sanjay</creator><creator>Jumaan, Aisha O</creator><creator>Vos, Theo</creator><creator>Hay, Simon I</creator><creator>Naghavi, Mohsen</creator><creator>Murray, Christopher J.L</creator><general>Springer International Publishing</general><scope>3HK</scope></search><sort><creationdate>2018</creationdate><title>Burden of diarrhea in the Eastern Mediterranean Region, 1990-2015: Findings from the Global Burden of Disease 2015 study</title><author>Mokdad, Ali H ; Khalil, Ibrahim ; El Bcheraoui, Charbel ; Moradi-Lakeh, Maziar ; Afshin, Ashkan ; Kassebaum, Nicholas J ; Chew, Adrienne ; Daoud, Farah ; Foreman, Kyle J ; Godwin, William W ; Kutz, Michael ; Troeger, Christopher ; Wang, Haidong ; Abu-Raddad, Laith J ; Ahmad Kiadaliri, Aliasghar ; Ahmadi, Alireza ; Alam, Khurshid ; Alizadeh-Navaei, Reza ; Al-Raddadi, Rajaa ; Altirkawi, Khalid A ; Alvis-Guzman, Nelson ; Anber, Nahla ; Anwari, Palwasha ; Mehari Atey, Tesfay ; Avokpaho, Euripide Frinel G. Arthur ; Bazargan-Hejazi, Shahrzad ; Bedi, Neeraj ; Bensenor, Isabela M ; Berhane, Adugnaw ; Shunu Beyene, Addisu ; Bhutta, Zulfiqar A ; Colin Buckle, Geoffrey ; Butt, Zahid A ; Danawi, Hadi ; Deribew, Amare ; Djalalinia, Shirin ; Dubey, Manisha ; Endries, Aman Yesuf ; Fereshtehnejad, Seyed-Mohammad ; Fischer, Florian ; Tewelde Gebrehiwot, Tsegaye ; Ribhi Hamadeh, Randah ; Hamidi, Samer ; Husseini, Abdullatif ; James, Spencer Lewis ; Jonas, Jost B ; Kasaeian, Amir ; Saleh Khader, Yousef ; Ahmad Khan, Ejaz ; Khan, Gulfaraz ; Kopec, Jacek A ; Koyanagi, Ai ; Abdul Latif, Asma ; Abd El Razek, Hassan Magdy ; Abd El Razek, Mohammed Magdy ; Majdzadeh, Reza ; Majeed, Azeem ; Memish, Ziad A ; Tadese Mengistu, Desalegn ; Mohammed, Shafiu ; Murthy, Srinivas ; Pourmalek, Farshad ; Qorbani, Mostafa ; Radfar, Amir ; Rahimi-Movaghar, Vafa ; Kumar Rai, Rajesh ; Ram, Usha ; Laith Rawaf, David ; Rawaf, Salman ; Rezaei, Satar ; Roshandel, Gholamreza ; Safdarian, Mahdi ; Ali Sahraian, Mohammad ; Salamati, Payman ; Ramon Sanabria, Juan ; Ali Shaikh, Masood ; Shigematsu, Mika ; Sobaih, Badr H.A ; Sykes, Bryan L ; Tehrani-Banihashemi, Arash ; Temsah, Mohamad-Hani ; Sulieman Terkawi, Abdullah ; Tiruye, Tenaw Yimer ; Topor-Madry, Roman ; Vollset, Stein Emil ; Wakayo, Tolassa ; Shey Wiysonge, Charles ; Workicho, Abdulhalik ; Yaghoubi, Mohsen ; Yaseri, Mehdi ; Yenesew, Muluken ; Yonemoto, Naohiro ; Younis, Mustafa Z ; El Sayed Zaki, Maysaa ; Zodpey, Sanjay ; Jumaan, Aisha O ; Vos, Theo ; Hay, Simon I ; Naghavi, Mohsen ; Murray, Christopher J.L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-cristin_nora_1956_197433</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Burden of disease</topic><topic>Diarrheal diseases</topic><topic>Eastern Mediterranean Region</topic><toplevel>online_resources</toplevel><creatorcontrib>Mokdad, Ali H</creatorcontrib><creatorcontrib>Khalil, Ibrahim</creatorcontrib><creatorcontrib>El Bcheraoui, Charbel</creatorcontrib><creatorcontrib>Moradi-Lakeh, Maziar</creatorcontrib><creatorcontrib>Afshin, Ashkan</creatorcontrib><creatorcontrib>Kassebaum, Nicholas J</creatorcontrib><creatorcontrib>Chew, Adrienne</creatorcontrib><creatorcontrib>Daoud, Farah</creatorcontrib><creatorcontrib>Foreman, Kyle J</creatorcontrib><creatorcontrib>Godwin, William W</creatorcontrib><creatorcontrib>Kutz, Michael</creatorcontrib><creatorcontrib>Troeger, Christopher</creatorcontrib><creatorcontrib>Wang, Haidong</creatorcontrib><creatorcontrib>Abu-Raddad, Laith J</creatorcontrib><creatorcontrib>Ahmad Kiadaliri, Aliasghar</creatorcontrib><creatorcontrib>Ahmadi, Alireza</creatorcontrib><creatorcontrib>Alam, Khurshid</creatorcontrib><creatorcontrib>Alizadeh-Navaei, Reza</creatorcontrib><creatorcontrib>Al-Raddadi, Rajaa</creatorcontrib><creatorcontrib>Altirkawi, Khalid A</creatorcontrib><creatorcontrib>Alvis-Guzman, Nelson</creatorcontrib><creatorcontrib>Anber, Nahla</creatorcontrib><creatorcontrib>Anwari, Palwasha</creatorcontrib><creatorcontrib>Mehari Atey, Tesfay</creatorcontrib><creatorcontrib>Avokpaho, Euripide Frinel G. 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Arthur</au><au>Bazargan-Hejazi, Shahrzad</au><au>Bedi, Neeraj</au><au>Bensenor, Isabela M</au><au>Berhane, Adugnaw</au><au>Shunu Beyene, Addisu</au><au>Bhutta, Zulfiqar A</au><au>Colin Buckle, Geoffrey</au><au>Butt, Zahid A</au><au>Danawi, Hadi</au><au>Deribew, Amare</au><au>Djalalinia, Shirin</au><au>Dubey, Manisha</au><au>Endries, Aman Yesuf</au><au>Fereshtehnejad, Seyed-Mohammad</au><au>Fischer, Florian</au><au>Tewelde Gebrehiwot, Tsegaye</au><au>Ribhi Hamadeh, Randah</au><au>Hamidi, Samer</au><au>Husseini, Abdullatif</au><au>James, Spencer Lewis</au><au>Jonas, Jost B</au><au>Kasaeian, Amir</au><au>Saleh Khader, Yousef</au><au>Ahmad Khan, Ejaz</au><au>Khan, Gulfaraz</au><au>Kopec, Jacek A</au><au>Koyanagi, Ai</au><au>Abdul Latif, Asma</au><au>Abd El Razek, Hassan Magdy</au><au>Abd El Razek, Mohammed Magdy</au><au>Majdzadeh, Reza</au><au>Majeed, Azeem</au><au>Memish, Ziad A</au><au>Tadese Mengistu, Desalegn</au><au>Mohammed, Shafiu</au><au>Murthy, Srinivas</au><au>Pourmalek, Farshad</au><au>Qorbani, Mostafa</au><au>Radfar, Amir</au><au>Rahimi-Movaghar, Vafa</au><au>Kumar Rai, Rajesh</au><au>Ram, Usha</au><au>Laith Rawaf, David</au><au>Rawaf, Salman</au><au>Rezaei, Satar</au><au>Roshandel, Gholamreza</au><au>Safdarian, Mahdi</au><au>Ali Sahraian, Mohammad</au><au>Salamati, Payman</au><au>Ramon Sanabria, Juan</au><au>Ali Shaikh, Masood</au><au>Shigematsu, Mika</au><au>Sobaih, Badr H.A</au><au>Sykes, Bryan L</au><au>Tehrani-Banihashemi, Arash</au><au>Temsah, Mohamad-Hani</au><au>Sulieman Terkawi, Abdullah</au><au>Tiruye, Tenaw Yimer</au><au>Topor-Madry, Roman</au><au>Vollset, Stein Emil</au><au>Wakayo, Tolassa</au><au>Shey Wiysonge, Charles</au><au>Workicho, Abdulhalik</au><au>Yaghoubi, Mohsen</au><au>Yaseri, Mehdi</au><au>Yenesew, Muluken</au><au>Yonemoto, Naohiro</au><au>Younis, Mustafa Z</au><au>El Sayed Zaki, Maysaa</au><au>Zodpey, Sanjay</au><au>Jumaan, Aisha O</au><au>Vos, Theo</au><au>Hay, Simon I</au><au>Naghavi, Mohsen</au><au>Murray, Christopher J.L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Burden of diarrhea in the Eastern Mediterranean Region, 1990-2015: Findings from the Global Burden of Disease 2015 study</atitle><date>2018</date><risdate>2018</risdate><abstract>Objectives: Diarrheal diseases (DD) are an important cause of disease burden, especially in children in low-income settings. DD can also impact children’s potential livelihood through growth faltering, cognitive impairment, and other sequelae. Methods: As part of the Global Burden of Disease study, we estimated DD burden, and the burden attributable to specific risk factors and etiologies, in the Eastern Mediterranean Region (EMR) between 1990 and 2015. We calculated disability-adjusted life-years (DALYs)—the sum of years of life lost and years lived with disability—for both sexes and all ages. Results: We estimate that over 103,692 diarrhea deaths occurred in the EMR in 2015 (95% uncertainty interval: 87,018–124,692), and the mortality rate was 16.0 deaths per 100,000 persons (95% UI: 13.4–19.2). The majority of these deaths occurred in children under 5 (63.3%) (65,670 deaths, 95% UI: 53,640–79,486). DALYs per 100,000 ranged from 304 (95% UI 228–400) in Kuwait to 38,900 (95% UI 25,900–54,300) in Somalia. Conclusions: Our findings will guide evidence-based health policy decisions for interventions to achieve the ultimate goal of reducing the DD burden.</abstract><pub>Springer International Publishing</pub><oa>free_for_read</oa></addata></record>
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subjects Burden of disease
Diarrheal diseases
Eastern Mediterranean Region
title Burden of diarrhea in the Eastern Mediterranean Region, 1990-2015: Findings from the Global Burden of Disease 2015 study
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