G1m1 predominance of intrathecal virus-specific antibodies in multiple sclerosis

We have previously shown that plasmablasts of the G1m1 allotype of IgG1 are selectively enriched in the cerebrospinal fluid of G1m1/G1m3 heterozygous patients with multiple sclerosis, whereas both allotypes are equally used in neuroborreliosis. Here, we demonstrate a strong preference for the G1m1 a...

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Hauptverfasser: Tomescu-Baciu, Alina, Vartdal, Frode, Holmøy, Trygve, Vedeler, Christian A, Lossius, Peter Andreas Vold
Format: Artikel
Sprache:eng
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