The RNA-Binding Protein hnRNP K Mediates the Effect of BDNF on Dendritic mRNA Metabolism and Regulates Synaptic NMDA Receptors in Hippocampal Neurons

Brain-derived neurotrophic factor (BDNF) is an important mediator of long-term synaptic potentiation (LTP) in the hippocampus. The local effects of BDNF depend on the activation of translation activity, which requires the delivery of transcripts to the synapse. In this work, we found that neuronal a...

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Hauptverfasser:	Leal, Graciano, Comprido, Diogo, de Luca, Pasqualino, Morais, Eduardo, Rodrigues, Luís, Mele, Miranda, Santos, Ana R, Costa, Rui O, Pinto, Maria Joana, Patil, Sudarshan, Berentsen, Birgitte, Afonso, Pedro, Carreto, Laura, Li, Ka Wan, Pinheiro, Paulo, Almeida, Ramiro D, Santos, Manuel A. S, Bramham, Clive R, Duarte, Carlos B
Format:	Artikel
Sprache:	eng
Schlagworte:	BDNF local translation long-term synaptic potentiation neurotrophins NMDA receptors RNA transport
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