Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling

The majority of cancer patients with advanced disease experience weight loss, including loss of lean body mass. Severe weight loss is characteristic for cancer cachexia, a condition that significantly impairs functional status and survival. The underlying causes of cachexia are incompletely understo...

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Hauptverfasser: Pettersen, Kristine, Andersen, Sonja Benedikte, Degen, simone, Tadini, Valentina, Grosjean, Joel, Hatakeyama, Shinji, Tesfahun, Almaz Nigatu, Moestue, Siver Andreas, Kim, Jana, Nonstad, Unni, Romundstad, Pål Richard, Skorpen, Frank, Sørhaug, Sveinung, Amundsen, Tore, Grønberg, Bjørn Henning, Strasser, Florian, Stephens, Nathan, Hoem, Dag, Molven, Anders, Kaasa, Stein, Fearon, Kenneth, Jacobi, Carsten, Bjørkøy, Geir
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Sprache:eng
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