Cuticle integrity and biogenic amine synthesis in Caenorhabditis elegans require the cofactor tetrahydrobiopterin (BH4)

Tetrahydrobiopterin (BH4) is the natural cofactor of several enzymes widely distributed among eukaryotes, including aromatic amino acid hydroxylases (AAAHs), nitric oxide synthases (NOSs), and alkylglycerol monooxygenase (AGMO). We show here that the nematode Caenorhabditis elegans, which has three...

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Hauptverfasser:	Loer, Curtis M, Calvo, Ana C, Watschinger, Katrin, Werner-Felmayer, Gabriele, O'Rourke, Delia, Stroud, Dave, Tong, Amy, Gotenstein, Jennifer R, Chisholm, Andrew D, Hodgkin, Jonathan, Werner, Ernst R, Martinez, Aurora
Format:	Artikel
Sprache:	eng
Schlagworte:	AGMO alkylglycerol monooxygenase biopterin dopamine epidermis GTPCH serotonin
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