Not every estimate counts – evaluation of cell composition estimation approaches in brain bulk tissue data

Background: Variation in cell composition can dramatically impact analyses in bulk tissue samples. A commonly employed approach to mitigate this issue is to adjust statistical models using estimates of cell abundance derived directly from omics data. While an arsenal of estimation methods exists, th...

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Hauptverfasser: Toker, Lilah, Sanchez Nido, Gonzalo, Tzoulis, Charalampos
Format: Artikel
Sprache:eng
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