Synthetic Oligodeoxynucleotide CpG Motifs Activate Human Complement through Their Backbone Structure and Induce Complement-Dependent Cytokine Release

Bacterial and mitochondrial DNA, sharing an evolutionary origin, act as danger-associated molecular patterns in infectious and sterile inflammation. They both contain immunomodulatory CpG motifs. Interactions between CpG motifs and the complement system are sparsely described, and mechanisms of comp...

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Hauptverfasser:	de Boer, Eline, Sokolova, Marina, Quach, Huy Quang, Mc Adam, Karin Ekholt, Götz, Maximilian P, Chaban, Viktoriia, Vaage, Ingvar Jarle, Fageräng, Beatrice Linnea Christina, Woodruff, Trent M, Garred, Peter, Nilsson, Per, Mollnes, Tom Eirik, Pischke, Soeren
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Sprache:	eng
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