Nuclear upregulation of class I phosphoinositide 3-kinase p110β correlates with high 47S rRNA levels in cancer cells

The class I phosphoinositide 3-kinase (PI3K) catalytic subunits p110α and p110β are ubiquitously expressed but differently targeted in tumours. In cancer, PIK3CB (encoding p110β) is seldom mutated compared with PIK3CA (encoding p110α) but can contribute to tumorigenesis in certain PTEN-deficient tum...

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Hauptverfasser:	Mazloumi Gavgani, Fatemeh, Karlsson, Thomas, Tangen, Ingvild Løberg, Papdine Morovicz, Andrea, Arnesen, Victoria Smith, Turcu, Diana Cornelia, Ninzima, Sandra, Spang, Katharina Maria, Krakstad, Camilla, Guillermet-Guibert, Julie, Lewis, Aurelia Eva
Format:	Artikel
Sprache:	eng
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