Targeting Cancer Chemotherapy Resistance by Precision Medicine-Driven Nanoparticle-Formulated Cisplatin

Therapy resistance is the major cause of cancer death. As patients respond heterogeneously, precision/personalized medicine needs to be considered, including the application of nanoparticles (NPs). The success of therapeutic NPs requires to first identify clinically relevant resistance mechanisms an...

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Veröffentlicht in:	ACS nano 2021-11, Vol.15 (11), p.18541-18556
Hauptverfasser:	Siemer, Svenja, Bauer, Tobias A, Scholz, Paul, Breder, Christina, Fenaroli, Federico, Harms, Gregory, Dietrich, Dimo, Dietrich, Jörn, Rosenauer, Christine, Barz, Matthias, Becker, Sven, Strieth, Sebastian, Reinhardt, Christoph, Fauth, Torsten, Hagemann, Jan, Stauber, Roland H
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Cell Line, Tumor Cisplatin - pharmacology Drug Resistance, Neoplasm Humans Membrane Proteins - metabolism Nanoparticles Neoplasms - drug therapy Precision Medicine Prospective Studies
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