The hypotonic environmental changes affect liposomal formulations for nose-to-brain targeted drug delivery

Systemic administration of drugs is ineffective in the treatment of central nervous system disorders because of the blood-brain barrier. Nasal administration has been suggested as an alternative administration route as drugs absorbed in the olfactory epithelium bypass the blood-brain barrier and rea...

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Veröffentlicht in:Journal of pharmaceutical sciences 2019
Hauptverfasser: Wu, Iren Yeeling, Nikolaisen, Trygg Einar, Skalko-Basnet, Natasa, Di Cagno, Massimiliano Pio
Format: Artikel
Sprache:nor
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