Synapse-specific changes in Arc and BDNF in rat hippocampus following chronic temporal lobe epilepsy

Expression of immediate early genes (IEGs) in the brain is important for synaptic plasticity, and probably also in neurodegenerative conditions. To understand the cellular mechanisms of the underlying neuropathophysiological processes in epilepsy, we need to pinpoint changes in concentration of syna...

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Veröffentlicht in:	Neuroscience research 2023-06, Vol.191, p.1-12
Hauptverfasser:	Egbenya, Daniel L., Hussain, Suleman, Lai, Yi-Chen, Anderson, Anne E., Davanger, Svend
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arc BDNF Brain-Derived Neurotrophic Factor - metabolism Chronic TLE Electron microscopy Epilepsy - metabolism Epilepsy, Temporal Lobe - chemically induced Epilepsy, Temporal Lobe - metabolism Hippocampus - metabolism Rats Synapse Synapses - physiology
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