DNA ploidy and PTEN as biomarkers for predicting aggressive disease in prostate cancer patients under active surveillance

Background Current risk stratification tools for prostate cancer patients under active surveillance (AS) may inadequately identify those needing treatment. We investigated DNA ploidy and PTEN as potential biomarkers to predict aggressive disease in AS patients. Methods We assessed DNA ploidy by imag...

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Veröffentlicht in:	British journal of cancer 2024-09, Vol.131 (5), p.895-904
Hauptverfasser:	Cyll, Karolina, Skaaheim Haug, Erik, Pradhan, Manohar, Vlatkovic, Ljiljana, Carlsen, Birgitte, Löffeler, Sven, Kildal, Wanja, Skogstad, Karin, Hauge Torkelsen, Frida, Syvertsen, Rolf Anders, Askautrud, Hanne A., Liestøl, Knut, Kleppe, Andreas, Danielsen, Håvard E.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/211 631/67/1857 631/67/2329 692/4028/67/1244 692/4028/67/589/466 Aged Biomarkers Biomarkers, Tumor - genetics Biomedical and Life Sciences Biomedicine Cancer Research Deoxyribonucleic acid DNA DNA, Neoplasm - genetics Drug Resistance Epidemiology Humans Immunohistochemistry Male Middle Aged Molecular Medicine Oncology Patients Ploidies Ploidy Prognosis Prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology PTEN Phosphohydrolase - genetics PTEN protein Risk assessment Surveillance Tumors Watchful Waiting
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