Recombinant human activated protein C attenuates endotoxin-induced lung injury in awake sheep

Introduction: Acute lung injury often complicates severe sepsis. In Gram-negative sepsis, bacterial endotoxin activates both coagulation and inflammation. Enhanced lung vascular pressures and permeability, increased extravascular lung water content and deteriorated gas exchange characterize ovine en...

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Hauptverfasser:	Wærhaug, Kristine, Langbakk, Bodil, Kuklin, Vladimir N, Kirov, Mikhail Y, Sovershaev, Mikhail, Ingebretsen, Ole C, Ytrehus, Kirsti, Bjertnæs, Lars J
Format:	Artikel
Sprache:	eng
Schlagworte:	Clinical medical disciplines: 750 Lung diseases: 777 Medical disciplines: 700 VDP
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