Raman spectroscopy for early real-time endoscopic optical diagnosis based on biochemical changes during the carcinogenesis of Barrett’s esophagus
Raman spectroscopy is a spectroscopic technique based on the inelastic scattering of monochromatic light that represents the molecular composition of the interrogated volume to provide a direct molecular fingerprint. Several investigations have revealed that confocal Raman spectroscopy can different...
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Veröffentlicht in: | 世界胃肠内镜杂志:英文版(电子版) 2016 (5), p.273-275 |
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creator | Hong Shi Su-Yu Chen Kai Lin |
description | Raman spectroscopy is a spectroscopic technique based on the inelastic scattering of monochromatic light that represents the molecular composition of the interrogated volume to provide a direct molecular fingerprint. Several investigations have revealed that confocal Raman spectroscopy can differentiate non-dysplastic Barrett’s esophagus from esophageal high-grade dysplasia and adenocarcinoma with high sensitivity and specificity. An automated on-line Raman spectral diagnostic system has made it possible to use Raman spectroscopy to guide accurate target biopsy instead of multiple random forceps-biopsies,this novel system is expected to improve in vivo precancerous diagnosis and tissue characterization of Barrett’s esophagus. |
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identifier | ISSN: 1948-5190 |
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issn | 1948-5190 1948-5190 |
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source | Baishideng "World Journal of" online journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
subjects | dysplasia Diagnosis esophagus Confocal High-grade Raman spectroscopy Barrett’s |
title | Raman spectroscopy for early real-time endoscopic optical diagnosis based on biochemical changes during the carcinogenesis of Barrett’s esophagus |
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