Lost in Redundancy： Dysfunctional Sperm Found Victim of Failed Histone Replacement Caused by Mutant Human Piwi

Male infertility, an issue that has aroused global concern in an era marked with ageing ,population and low birthrate, to a large extent results from decreased quantity and worsened quality of sperm, according to experts. An extreme case is idiopathic azoospermia, a medical condition featuring no sp...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	中国科学院院刊：英文版 2017, Vol.31 (2), p.91-95
1. Verfasser:	SONG Jianlan
Format:	Artikel
Sprache:	eng
Schlagworte:	Human 人口出生率人口老龄化冗余受害者精子数量组蛋白靶向治疗
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page	95
container_issue	2
container_start_page	91
container_title	中国科学院院刊：英文版
container_volume	31
creator	SONG Jianlan
description	Male infertility, an issue that has aroused global concern in an era marked with ageing ,population and low birthrate, to a large extent results from decreased quantity and worsened quality of sperm, according to experts. An extreme case is idiopathic azoospermia, a medical condition featuring no sperm in semen. This remains an obstinate disease that has perplexed scientists, as its underlying mechanisms are far from clear and hence no well- targeted treatment strategy is available, let alone any effective therapy or medicine.
format	Article
fullrecord	<record><control><sourceid>chongqing</sourceid><recordid>TN_cdi_chongqing_primary_672957140</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cqvip_id>672957140</cqvip_id><sourcerecordid>672957140</sourcerecordid><originalsourceid>FETCH-chongqing_primary_6729571403</originalsourceid><addsrcrecordid>eNqNjEGKwkAQRXvhgDp6h8K90DHG4FoNWSgM4zDbUCYdLUlXx3Q3kqt4Fu_kFaYXcwBXH95_vIEYRVLG8zhJF0MxtvYqZRIl8Xok2r2xDojhW1WeK-Syfz0fsO1t7bl0ZBgbOLaq05CZIMAvBarB1JAhNaqCnKwzrEKgbbBUWrGDDXobrlMPB-8wgNxrZPiiO03ER42NVdP__RSzbPezyeflxfD5Rnwu2o40dn2xShfrJI2WMn5L-gM6ckoH</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Lost in Redundancy： Dysfunctional Sperm Found Victim of Failed Histone Replacement Caused by Mutant Human Piwi</title><source>Alma/SFX Local Collection</source><creator>SONG Jianlan</creator><creatorcontrib>SONG Jianlan</creatorcontrib><description>Male infertility, an issue that has aroused global concern in an era marked with ageing ,population and low birthrate, to a large extent results from decreased quantity and worsened quality of sperm, according to experts. An extreme case is idiopathic azoospermia, a medical condition featuring no sperm in semen. This remains an obstinate disease that has perplexed scientists, as its underlying mechanisms are far from clear and hence no well- targeted treatment strategy is available, let alone any effective therapy or medicine.</description><identifier>ISSN: 1003-3572</identifier><language>eng</language><subject>Human ; 人口出生率 ; 人口老龄化 ; 冗余 ; 受害者 ; 精子数量 ; 组蛋白 ; 靶向治疗</subject><ispartof>中国科学院院刊：英文版, 2017, Vol.31 (2), p.91-95</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/86621X/86621X.jpg</thumbnail><link.rule.ids>314,776,780,4010</link.rule.ids></links><search><creatorcontrib>SONG Jianlan</creatorcontrib><title>Lost in Redundancy： Dysfunctional Sperm Found Victim of Failed Histone Replacement Caused by Mutant Human Piwi</title><title>中国科学院院刊：英文版</title><addtitle>Bulletin of the Chinese Academy of Sciences</addtitle><description>Male infertility, an issue that has aroused global concern in an era marked with ageing ,population and low birthrate, to a large extent results from decreased quantity and worsened quality of sperm, according to experts. An extreme case is idiopathic azoospermia, a medical condition featuring no sperm in semen. This remains an obstinate disease that has perplexed scientists, as its underlying mechanisms are far from clear and hence no well- targeted treatment strategy is available, let alone any effective therapy or medicine.</description><subject>Human</subject><subject>人口出生率</subject><subject>人口老龄化</subject><subject>冗余</subject><subject>受害者</subject><subject>精子数量</subject><subject>组蛋白</subject><subject>靶向治疗</subject><issn>1003-3572</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNqNjEGKwkAQRXvhgDp6h8K90DHG4FoNWSgM4zDbUCYdLUlXx3Q3kqt4Fu_kFaYXcwBXH95_vIEYRVLG8zhJF0MxtvYqZRIl8Xok2r2xDojhW1WeK-Syfz0fsO1t7bl0ZBgbOLaq05CZIMAvBarB1JAhNaqCnKwzrEKgbbBUWrGDDXobrlMPB-8wgNxrZPiiO03ER42NVdP__RSzbPezyeflxfD5Rnwu2o40dn2xShfrJI2WMn5L-gM6ckoH</recordid><startdate>2017</startdate><enddate>2017</enddate><creator>SONG Jianlan</creator><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>~WA</scope></search><sort><creationdate>2017</creationdate><title>Lost in Redundancy： Dysfunctional Sperm Found Victim of Failed Histone Replacement Caused by Mutant Human Piwi</title><author>SONG Jianlan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-chongqing_primary_6729571403</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Human</topic><topic>人口出生率</topic><topic>人口老龄化</topic><topic>冗余</topic><topic>受害者</topic><topic>精子数量</topic><topic>组蛋白</topic><topic>靶向治疗</topic><toplevel>online_resources</toplevel><creatorcontrib>SONG Jianlan</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库- 镜像站点</collection><jtitle>中国科学院院刊：英文版</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SONG Jianlan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lost in Redundancy： Dysfunctional Sperm Found Victim of Failed Histone Replacement Caused by Mutant Human Piwi</atitle><jtitle>中国科学院院刊：英文版</jtitle><addtitle>Bulletin of the Chinese Academy of Sciences</addtitle><date>2017</date><risdate>2017</risdate><volume>31</volume><issue>2</issue><spage>91</spage><epage>95</epage><pages>91-95</pages><issn>1003-3572</issn><abstract>Male infertility, an issue that has aroused global concern in an era marked with ageing ,population and low birthrate, to a large extent results from decreased quantity and worsened quality of sperm, according to experts. An extreme case is idiopathic azoospermia, a medical condition featuring no sperm in semen. This remains an obstinate disease that has perplexed scientists, as its underlying mechanisms are far from clear and hence no well- targeted treatment strategy is available, let alone any effective therapy or medicine.</abstract></addata></record>
fulltext	fulltext
identifier	ISSN: 1003-3572
ispartof	中国科学院院刊：英文版, 2017, Vol.31 (2), p.91-95
issn	1003-3572
language	eng
recordid	cdi_chongqing_primary_672957140
source	Alma/SFX Local Collection
subjects	Human 人口出生率人口老龄化冗余受害者精子数量组蛋白靶向治疗
title	Lost in Redundancy： Dysfunctional Sperm Found Victim of Failed Histone Replacement Caused by Mutant Human Piwi
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-15T06%3A46%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-chongqing&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Lost%20in%20Redundancy%EF%BC%9A%20Dysfunctional%20Sperm%20Found%20Victim%20of%20Failed%20Histone%20Replacement%20Caused%20by%20Mutant%20Human%20Piwi&rft.jtitle=%E4%B8%AD%E5%9B%BD%E7%A7%91%E5%AD%A6%E9%99%A2%E9%99%A2%E5%88%8A%EF%BC%9A%E8%8B%B1%E6%96%87%E7%89%88&rft.au=SONG%20Jianlan&rft.date=2017&rft.volume=31&rft.issue=2&rft.spage=91&rft.epage=95&rft.pages=91-95&rft.issn=1003-3572&rft_id=info:doi/&rft_dat=%3Cchongqing%3E672957140%3C/chongqing%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_cqvip_id=672957140&rfr_iscdi=true