High-resolution cryo-EM structure of the proteasome in complex with ADP-AIFx

The 26S proteasome is an ATP-dependent dynamic 2.5 MDa protease that regulates numerous essential cellular functions through degradation of ubiquitinated substrates. Here we present a near-atomic-resolution cryo-EM map of the S. cerevisiae 26S proteasome in complex with ADP-AIFx. Our biochemical and...

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Veröffentlicht in:	细胞研究：英文版 2017, Vol.27 (3), p.373-385
1. Verfasser:	Zhanyu Ding Zhenglin Fu Cong Xu Yifan Wang Yanxing Wang Junrui Li Liangliang Kong Jinhuan Chen Na Li Rongguang Zhang Yao Cong
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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