miR-181b functions as an oncomiR in colorectal cancer by targeting PDCDZ

Programmed cell death 4 （PDCD4） is a RNA-binding protein that acts as a tumor suppressor in many cancer types, including colorectal cancer （CRC）. During CRC carcinogenesis, PDCD4 protein levels remarkably decrease, but the underlying molecular mechanism for decreased PDCD4 expression is not fully un...

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Veröffentlicht in:	蛋白质与细胞：英文版 2016 (10), p.722-734
1. Verfasser:	Yanqing Liu Uzair-ur-Rehman Yu Guo Hongwei Liang Rongjie Cheng Fei Yang Yeting Hong Chihao Zhao Minghui Liu Mengchao Yu Xinyan Zhou Kai Yin Jiangning Chen Junfeng Zhang Chen-Yu Zhang Feng Zhi Xi Chen
Format:	Artikel
Sprache:	eng
Schlagworte:	miRNA RNA结合蛋白 STAT3 分子机制 大肠癌 细胞活化 结直肠癌 肿瘤抑制基因
Online-Zugang:	Volltext
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