Radiotherapy for gynecologic cancerin nonagenarian patients:a framework for new paradigms

No consensus exists regarding the role of radiotherapy in the management of gynecologic cancer in nonagenarian patients.We retrospectively reviewed the outcomes of 19 consecutive nonagenarian patients with gynecologic cancer(6 endometrial cancers,6 cervical cancers,4 vulvar cancers,and 3 vaginal can...

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Veröffentlicht in:癌症:英文版 2016, Vol.35 (7), p.382-384
1. Verfasser: Benoite Mry Sylvie Mengue Ndong Jean-Baptiste Guy Avi Assouline Alexander T.Falk Ana?s Valeille Jane-Chloc Trone Romain Rivoirard Pierre Auberdiac Alexis Vallard Sophie Espenel Guillaume Moriceau Olivier Collard Claire Bosacki Jean-Philippe Jacquin Guy de Laroche Pierre Fournel Cyrus Chargari Nicolas Magn
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creator Benoite Mry Sylvie Mengue Ndong Jean-Baptiste Guy Avi Assouline Alexander T.Falk Ana?s Valeille Jane-Chloc Trone Romain Rivoirard Pierre Auberdiac Alexis Vallard Sophie Espenel Guillaume Moriceau Olivier Collard Claire Bosacki Jean-Philippe Jacquin Guy de Laroche Pierre Fournel Cyrus Chargari Nicolas Magn
description No consensus exists regarding the role of radiotherapy in the management of gynecologic cancer in nonagenarian patients.We retrospectively reviewed the outcomes of 19 consecutive nonagenarian patients with gynecologic cancer(6 endometrial cancers,6 cervical cancers,4 vulvar cancers,and 3 vaginal cancers) who were treated with radiotherapy.Radiotherapy was performed mainly in a palliative setting(n = 12;63.2%),with a median dose of 45 Gy(range,6-76 Gy).Infrequent major acute or late toxicities were reported.Among 19 patients,9(47.4%) experienced tumor progression,5(26.3%) experienced complete response,2(10.5%) experienced stable disease and/or partial response.At last follow-up,12 patients(63.2%) had died;most deaths(n = 9) occurred because of the cancer.These results suggest that radiotherapy is feasible in the treatment of nonagenarian patients with gynecologic cancer.
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subjects 妇科
子宫内膜癌
放射治疗
放疗
框架
癌症患者
肿瘤患者
肿瘤治疗
title Radiotherapy for gynecologic cancerin nonagenarian patients:a framework for new paradigms
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