Identification of a novel HIV-1 intra-circulating recombinant form 01_AE in China: a descendant of the previously identified CRF01 AE transmission clusters I and 6
Dear Editors, Here, we report a novel HIV-1 intra-circulating recombinant form 01_AE (intra-CRF01_AE: CRF01-1AE/CRF01-6AE) composed of CRF01_AE transmission clusters 1 and 6, which was identified in a heterosexual male from Fujian, with one breakpoint observed in the vif gene. The CRF01_AE region I...
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creator | NING ChuanYi LI XingGuang TANG WeiMing ZHOU go CAI WeiPing TUCKER Joseph D |
description | Dear Editors,
Here, we report a novel HIV-1 intra-circulating recombinant form 01_AE (intra-CRF01_AE: CRF01-1AE/CRF01-6AE) composed of CRF01_AE transmission clusters 1 and 6, which was identified in a heterosexual male from Fujian, with one breakpoint observed in the vif gene. The CRF01_AE region I (HXB2: 868-5184) of the recombinant clustered with CRF01_AE transmission cluster 1, which is mainly circulating among injection drug users (IDUs) and heterosexuals in southern and southwestern China, with the support of a 100% bootstrap value. The CRF01_AE region II (HXB2: 5185-9605) of the recombinant clustered with CRF01_AE transmission cluster 6, which mainly prevails among heterosexuals in southern China, with the support of a 100% bootstrap value. To our knowledge, this is the first detection of a novel HIV-1 intra-CRF01_AE recombinant form (CRF01-1_AE/CRF01-6_ AE) in Fujian, China, which indicates ongoing active HIV-1 transmission among heter- osexuals in this region. |
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Here, we report a novel HIV-1 intra-circulating recombinant form 01_AE (intra-CRF01_AE: CRF01-1AE/CRF01-6AE) composed of CRF01_AE transmission clusters 1 and 6, which was identified in a heterosexual male from Fujian, with one breakpoint observed in the vif gene. The CRF01_AE region I (HXB2: 868-5184) of the recombinant clustered with CRF01_AE transmission cluster 1, which is mainly circulating among injection drug users (IDUs) and heterosexuals in southern and southwestern China, with the support of a 100% bootstrap value. The CRF01_AE region II (HXB2: 5185-9605) of the recombinant clustered with CRF01_AE transmission cluster 6, which mainly prevails among heterosexuals in southern China, with the support of a 100% bootstrap value. To our knowledge, this is the first detection of a novel HIV-1 intra-CRF01_AE recombinant form (CRF01-1_AE/CRF01-6_ AE) in Fujian, China, which indicates ongoing active HIV-1 transmission among heter- osexuals in this region.</description><identifier>ISSN: 1674-7305</identifier><identifier>EISSN: 1869-1889</identifier><language>eng</language><subject>HIV-1 ; 传输集群 ; 后代 ; 识别 ; 重组</subject><ispartof>中国科学:生命科学英文版, 2015 (7), p.724-726</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/60112X/60112X.jpg</thumbnail><link.rule.ids>315,781,785,4025</link.rule.ids></links><search><creatorcontrib>NING ChuanYi LI XingGuang TANG WeiMing ZHOU go CAI WeiPing TUCKER Joseph D</creatorcontrib><title>Identification of a novel HIV-1 intra-circulating recombinant form 01_AE in China: a descendant of the previously identified CRF01 AE transmission clusters I and 6</title><title>中国科学:生命科学英文版</title><description>Dear Editors,
Here, we report a novel HIV-1 intra-circulating recombinant form 01_AE (intra-CRF01_AE: CRF01-1AE/CRF01-6AE) composed of CRF01_AE transmission clusters 1 and 6, which was identified in a heterosexual male from Fujian, with one breakpoint observed in the vif gene. The CRF01_AE region I (HXB2: 868-5184) of the recombinant clustered with CRF01_AE transmission cluster 1, which is mainly circulating among injection drug users (IDUs) and heterosexuals in southern and southwestern China, with the support of a 100% bootstrap value. The CRF01_AE region II (HXB2: 5185-9605) of the recombinant clustered with CRF01_AE transmission cluster 6, which mainly prevails among heterosexuals in southern China, with the support of a 100% bootstrap value. To our knowledge, this is the first detection of a novel HIV-1 intra-CRF01_AE recombinant form (CRF01-1_AE/CRF01-6_ AE) in Fujian, China, which indicates ongoing active HIV-1 transmission among heter- osexuals in this region.</description><subject>HIV-1</subject><subject>传输集群</subject><subject>后代</subject><subject>识别</subject><subject>重组</subject><issn>1674-7305</issn><issn>1869-1889</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNqNjkFOwzAQRS0EEhX0DiP2lmxMnGSJolbNFiG2kbGdxsgZF9up1Kuw5xbciSvgSj0As5nR15v__xVZ8Ua2lDdNe11uWT_RWrDqlqxT-mBlhGCPdb0i372xmN3otMouIIQRFGA4Wg-7_o1ycJijotpFvfiC4B6i1WF-d6gwwxjiDIwPz5sCQjcV9ffnq1gYm7RFc2aKZZ4sHKI9urAkfwJ3ybQGupct41DeSwqm2aV0bqH9krKNCXpQaEDek5tR-WTXl31HHrab125H9RRw_1laDYfoZhVPg5SVELwVlfgX9Ad8i15W</recordid><startdate>2015</startdate><enddate>2015</enddate><creator>NING ChuanYi LI XingGuang TANG WeiMing ZHOU go CAI WeiPing TUCKER Joseph D</creator><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>~WA</scope></search><sort><creationdate>2015</creationdate><title>Identification of a novel HIV-1 intra-circulating recombinant form 01_AE in China: a descendant of the previously identified CRF01 AE transmission clusters I and 6</title><author>NING ChuanYi LI XingGuang TANG WeiMing ZHOU go CAI WeiPing TUCKER Joseph D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-chongqing_primary_6653319353</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>HIV-1</topic><topic>传输集群</topic><topic>后代</topic><topic>识别</topic><topic>重组</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>NING ChuanYi LI XingGuang TANG WeiMing ZHOU go CAI WeiPing TUCKER Joseph D</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库- 镜像站点</collection><jtitle>中国科学:生命科学英文版</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>NING ChuanYi LI XingGuang TANG WeiMing ZHOU go CAI WeiPing TUCKER Joseph D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Identification of a novel HIV-1 intra-circulating recombinant form 01_AE in China: a descendant of the previously identified CRF01 AE transmission clusters I and 6</atitle><jtitle>中国科学:生命科学英文版</jtitle><date>2015</date><risdate>2015</risdate><issue>7</issue><spage>724</spage><epage>726</epage><pages>724-726</pages><issn>1674-7305</issn><eissn>1869-1889</eissn><abstract>Dear Editors,
Here, we report a novel HIV-1 intra-circulating recombinant form 01_AE (intra-CRF01_AE: CRF01-1AE/CRF01-6AE) composed of CRF01_AE transmission clusters 1 and 6, which was identified in a heterosexual male from Fujian, with one breakpoint observed in the vif gene. The CRF01_AE region I (HXB2: 868-5184) of the recombinant clustered with CRF01_AE transmission cluster 1, which is mainly circulating among injection drug users (IDUs) and heterosexuals in southern and southwestern China, with the support of a 100% bootstrap value. The CRF01_AE region II (HXB2: 5185-9605) of the recombinant clustered with CRF01_AE transmission cluster 6, which mainly prevails among heterosexuals in southern China, with the support of a 100% bootstrap value. To our knowledge, this is the first detection of a novel HIV-1 intra-CRF01_AE recombinant form (CRF01-1_AE/CRF01-6_ AE) in Fujian, China, which indicates ongoing active HIV-1 transmission among heter- osexuals in this region.</abstract></addata></record> |
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source | SpringerNature Journals; Alma/SFX Local Collection |
subjects | HIV-1 传输集群 后代 识别 重组 |
title | Identification of a novel HIV-1 intra-circulating recombinant form 01_AE in China: a descendant of the previously identified CRF01 AE transmission clusters I and 6 |
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