Synthesis of 2,5-disubstitued benzimidazole using SnC12-catalyzed reduction system at room temperature

Stannous chloride dihydrate is used as an efficient catalyst in reductive cyclization of 2-nitro-5- substituted aniline Schiff base leading to stable 2,5-disubstitued benzimidazole derivatives in excellent yields with good purity. It provides a novel method of synthesis of 2,5-disubstitued benzimida...

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Veröffentlicht in:中国化学快报:英文版 2014 (1), p.155-158
1. Verfasser: Li-Ping Duan Qiang Li Ning-Bo Wu Dong-Fang Xu Hao-Bing Zhang
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description Stannous chloride dihydrate is used as an efficient catalyst in reductive cyclization of 2-nitro-5- substituted aniline Schiff base leading to stable 2,5-disubstitued benzimidazole derivatives in excellent yields with good purity. It provides a novel method of synthesis of 2,5-disubstitued benzimidazole under reductive system at room temperature.
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source ScienceDirect Journals (5 years ago - present); Alma/SFX Local Collection
subjects 二取代
二水合物
取代苯并咪唑
合成
室温
苯并咪唑衍生物
还原系统
高效催化剂
title Synthesis of 2,5-disubstitued benzimidazole using SnC12-catalyzed reduction system at room temperature
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