Chemical constituents from the submerged plant Potamogeton crispus and.. their effects on NAD（P）H：quinone oxidoreductase 1
A new isopimarane-type diterpene （liwariverol, 1） and eight known compounds were isolated and characterized from the EtOAc extract of the whole plant of Potamogeton crispus. The structure of 1 was elucidated to be 17-hydroxy-8c~H-isopimara-9（11）,15- diene by means of spectroscopic methods. Among the...
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| Veröffentlicht in: | 中国化学快报：英文版 2012, Vol.23 (10), p.1157-1160 |
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| container_title | 中国化学快报：英文版 |
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| creator | Miao Ye Jun Zhi Ma Juan Xiong Shu Ting Liu Dong Wang Chong Gang Yuan Ji Yan Ma Jin Feng Hu |
| description | A new isopimarane-type diterpene （liwariverol, 1） and eight known compounds were isolated and characterized from the EtOAc extract of the whole plant of Potamogeton crispus. The structure of 1 was elucidated to be 17-hydroxy-8c~H-isopimara-9（11）,15- diene by means of spectroscopic methods. Among the isolates, crenulatoside A （2）, an acyclic sesquiterpene glycoside, was found to have anti-oxidative activity with enhancement of the expression of the NAD（P）H：quinone oxidoreductase 1 （NQO1） in human neuroblastoma SH-SY5Y cells at 100 μmol/L after a 24-h incubation. |
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The structure of 1 was elucidated to be 17-hydroxy-8c~H-isopimara-9（11）,15- diene by means of spectroscopic methods. Among the isolates, crenulatoside A （2）, an acyclic sesquiterpene glycoside, was found to have anti-oxidative activity with enhancement of the expression of the NAD（P）H：quinone oxidoreductase 1 （NQO1） in human neuroblastoma SH-SY5Y cells at 100 μmol/L after a 24-h incubation.</description><identifier>ISSN: 1001-8417</identifier><identifier>EISSN: 1878-5964</identifier><language>eng</language><subject>NAD ; SH-SY5Y细胞 ; 乙酸乙酯提取物 ; 化学成分 ; 氧化还原酶 ; 沉水植物 ; 神经母细胞瘤 ; 菹草</subject><ispartof>中国化学快报：英文版, 2012, Vol.23 (10), p.1157-1160</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/84039X/84039X.jpg</thumbnail><link.rule.ids>314,776,780,4010</link.rule.ids></links><search><creatorcontrib>Miao Ye Jun Zhi Ma Juan Xiong Shu Ting Liu Dong Wang Chong Gang Yuan Ji Yan Ma Jin Feng Hu</creatorcontrib><title>Chemical constituents from the submerged plant Potamogeton crispus and.. their effects on NAD（P）H：quinone oxidoreductase 1</title><title>中国化学快报：英文版</title><addtitle>Chinese Chemical Letters</addtitle><description>A new isopimarane-type diterpene （liwariverol, 1） and eight known compounds were isolated and characterized from the EtOAc extract of the whole plant of Potamogeton crispus. 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Among the isolates, crenulatoside A （2）, an acyclic sesquiterpene glycoside, was found to have anti-oxidative activity with enhancement of the expression of the NAD（P）H：quinone oxidoreductase 1 （NQO1） in human neuroblastoma SH-SY5Y cells at 100 μmol/L after a 24-h incubation.</description><subject>NAD</subject><subject>SH-SY5Y细胞</subject><subject>乙酸乙酯提取物</subject><subject>化学成分</subject><subject>氧化还原酶</subject><subject>沉水植物</subject><subject>神经母细胞瘤</subject><subject>菹草</subject><issn>1001-8417</issn><issn>1878-5964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNqNjD1Ow0AQRleISATCHYYDOLJjYy8lCqBUKAV9tKzH9iLvjLM_EnSUcAXO4jv5CjgSB6D6nvSevjOxzGQlk9u7sjifOU2zRBZZdSEuvX9L042UebkUn9sOrdGqB83kgwkRKXhoHFsIHYKPrxZdizUMvaIAew7KcouBCbQzfogeFNXr9ak2DrBpUM8Hs36-f5jGr_00fu-m8ecYDTEh8Lup2WEddVAeIVuJRaN6j9d_eyVunh5ftrtEd0zt0VB7GJyxyn0cirzKZbmp8v80v_wRVIc</recordid><startdate>2012</startdate><enddate>2012</enddate><creator>Miao Ye Jun Zhi Ma Juan Xiong Shu Ting Liu Dong Wang Chong Gang Yuan Ji Yan Ma Jin Feng Hu</creator><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>~WA</scope></search><sort><creationdate>2012</creationdate><title>Chemical constituents from the submerged plant Potamogeton crispus and.. their effects on NAD（P）H：quinone oxidoreductase 1</title><author>Miao Ye Jun Zhi Ma Juan Xiong Shu Ting Liu Dong Wang Chong Gang Yuan Ji Yan Ma Jin Feng Hu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-chongqing_primary_437386273</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>NAD</topic><topic>SH-SY5Y细胞</topic><topic>乙酸乙酯提取物</topic><topic>化学成分</topic><topic>氧化还原酶</topic><topic>沉水植物</topic><topic>神经母细胞瘤</topic><topic>菹草</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Miao Ye Jun Zhi Ma Juan Xiong Shu Ting Liu Dong Wang Chong Gang Yuan Ji Yan Ma Jin Feng Hu</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库- 镜像站点</collection><jtitle>中国化学快报：英文版</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Miao Ye Jun Zhi Ma Juan Xiong Shu Ting Liu Dong Wang Chong Gang Yuan Ji Yan Ma Jin Feng Hu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Chemical constituents from the submerged plant Potamogeton crispus and.. their effects on NAD（P）H：quinone oxidoreductase 1</atitle><jtitle>中国化学快报：英文版</jtitle><addtitle>Chinese Chemical Letters</addtitle><date>2012</date><risdate>2012</risdate><volume>23</volume><issue>10</issue><spage>1157</spage><epage>1160</epage><pages>1157-1160</pages><issn>1001-8417</issn><eissn>1878-5964</eissn><abstract>A new isopimarane-type diterpene （liwariverol, 1） and eight known compounds were isolated and characterized from the EtOAc extract of the whole plant of Potamogeton crispus. The structure of 1 was elucidated to be 17-hydroxy-8c~H-isopimara-9（11）,15- diene by means of spectroscopic methods. Among the isolates, crenulatoside A （2）, an acyclic sesquiterpene glycoside, was found to have anti-oxidative activity with enhancement of the expression of the NAD（P）H：quinone oxidoreductase 1 （NQO1） in human neuroblastoma SH-SY5Y cells at 100 μmol/L after a 24-h incubation.</abstract></addata></record> |
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| identifier | ISSN: 1001-8417 |
| ispartof | 中国化学快报：英文版, 2012, Vol.23 (10), p.1157-1160 |
| issn | 1001-8417 1878-5964 |
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| source | Elsevier ScienceDirect Journals Complete; Alma/SFX Local Collection |
| subjects | NAD SH-SY5Y细胞 乙酸乙酯提取物 化学成分 氧化还原酶 沉水植物 神经母细胞瘤 菹草 |
| title | Chemical constituents from the submerged plant Potamogeton crispus and.. their effects on NAD（P）H：quinone oxidoreductase 1 |
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