Functional MRI study of mild Alzheimer's disease using amplitude of low frequency fluctuation analysis
Background Previous studies have shown that the functional brain activity in the resting state is impaired in Alzheimer's disease (AD) patients. However, most studies focused on the relationship between different brain areas, rather than the amplitude or strength of the regional brain activity. The...
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Veröffentlicht in: | 中华医学杂志:英文版 2012 (5), p.858-862 |
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creator | XI Qian ZHAO Xiao-hu WANG Pei-jun GUO Qi-hao YAN Chao-gan HE Yong |
description | Background Previous studies have shown that the functional brain activity in the resting state is impaired in Alzheimer's disease (AD) patients. However, most studies focused on the relationship between different brain areas, rather than the amplitude or strength of the regional brain activity. The purpose of this study was to explore the functional brain changes in AD patients by measuring the amplitude of the blood oxygenation level dependent (BOLD) functional MRI (fMRI) signals. |
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However, most studies focused on the relationship between different brain areas, rather than the amplitude or strength of the regional brain activity. The purpose of this study was to explore the functional brain changes in AD patients by measuring the amplitude of the blood oxygenation level dependent (BOLD) functional MRI (fMRI) signals.</description><identifier>ISSN: 0366-6999</identifier><identifier>EISSN: 2542-5641</identifier><language>eng</language><subject>低频 ; 功能变化 ; 功能磁共振成像 ; 大脑活动 ; 振幅 ; 波动分析 ; 阿尔茨海默氏病 ; 静止状态</subject><ispartof>中华医学杂志:英文版, 2012 (5), p.858-862</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/85656X/85656X.jpg</thumbnail><link.rule.ids>314,776,780,4010</link.rule.ids></links><search><creatorcontrib>XI Qian ZHAO Xiao-hu WANG Pei-jun GUO Qi-hao YAN Chao-gan HE Yong</creatorcontrib><title>Functional MRI study of mild Alzheimer's disease using amplitude of low frequency fluctuation analysis</title><title>中华医学杂志:英文版</title><addtitle>Chinese Medical Journal</addtitle><description>Background Previous studies have shown that the functional brain activity in the resting state is impaired in Alzheimer's disease (AD) patients. 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The purpose of this study was to explore the functional brain changes in AD patients by measuring the amplitude of the blood oxygenation level dependent (BOLD) functional MRI (fMRI) signals.</description><subject>低频</subject><subject>功能变化</subject><subject>功能磁共振成像</subject><subject>大脑活动</subject><subject>振幅</subject><subject>波动分析</subject><subject>阿尔茨海默氏病</subject><subject>静止状态</subject><issn>0366-6999</issn><issn>2542-5641</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNqNzE0KgkAYgOEhCrKfO3wdQPB31GVEUos20V4GHXViHH8-h7ALdKnu1BVS6ACt3s3DOyOG43uO6VPPnhPDcik1aRRFS7JCvFuW4_sBNUgZa5X2olZMwuV6Bux1NkCdQyVkBnv5LLmoePd5vxAygZwhB41CFcCqRopR80nL-gF5x1vNVTpALnXaazZtgY3nAQVuyCJnEvn21zXZxcfb4WSmZa2KdjwmTScq1g2JZ7tWYIeh-4_5AkN_Sco</recordid><startdate>2012</startdate><enddate>2012</enddate><creator>XI Qian ZHAO Xiao-hu WANG Pei-jun GUO Qi-hao YAN Chao-gan HE Yong</creator><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope></search><sort><creationdate>2012</creationdate><title>Functional MRI study of mild Alzheimer's disease using amplitude of low frequency fluctuation analysis</title><author>XI Qian ZHAO Xiao-hu WANG Pei-jun GUO Qi-hao YAN Chao-gan HE Yong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-chongqing_primary_413071883</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>低频</topic><topic>功能变化</topic><topic>功能磁共振成像</topic><topic>大脑活动</topic><topic>振幅</topic><topic>波动分析</topic><topic>阿尔茨海默氏病</topic><topic>静止状态</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>XI Qian ZHAO Xiao-hu WANG Pei-jun GUO Qi-hao YAN Chao-gan HE Yong</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><jtitle>中华医学杂志:英文版</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>XI Qian ZHAO Xiao-hu WANG Pei-jun GUO Qi-hao YAN Chao-gan HE Yong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Functional MRI study of mild Alzheimer's disease using amplitude of low frequency fluctuation analysis</atitle><jtitle>中华医学杂志:英文版</jtitle><addtitle>Chinese Medical Journal</addtitle><date>2012</date><risdate>2012</risdate><issue>5</issue><spage>858</spage><epage>862</epage><pages>858-862</pages><issn>0366-6999</issn><eissn>2542-5641</eissn><abstract>Background Previous studies have shown that the functional brain activity in the resting state is impaired in Alzheimer's disease (AD) patients. However, most studies focused on the relationship between different brain areas, rather than the amplitude or strength of the regional brain activity. The purpose of this study was to explore the functional brain changes in AD patients by measuring the amplitude of the blood oxygenation level dependent (BOLD) functional MRI (fMRI) signals.</abstract></addata></record> |
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source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
subjects | 低频 功能变化 功能磁共振成像 大脑活动 振幅 波动分析 阿尔茨海默氏病 静止状态 |
title | Functional MRI study of mild Alzheimer's disease using amplitude of low frequency fluctuation analysis |
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