Alterations of mitochondrial function in ischemia/reperfusion cat heart
The effect of myocardium being subjected to 60 min ischemia and 60 min reperfusion incat cardiopulmonary bypass on level of lipid peroxides(LPO),function of myocardial mitochon-dria and activity of superoxides dismutase(SOD)was studied. Myocardial mitochondrial functionwas depressed slightly 60 rain...
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| Veröffentlicht in: | 中国人民解放军军医大学学报：英文版 1993 (4), p.337-341 |
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| container_issue | 4 |
| container_start_page | 337 |
| container_title | 中国人民解放军军医大学学报：英文版 |
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| creator | 陈龙 张宝仁 朱家麟 陈如坤 郝家骅 陈晓晴 陈克明 |
| description | The effect of myocardium being subjected to 60 min ischemia and 60 min reperfusion incat cardiopulmonary bypass on level of lipid peroxides(LPO),function of myocardial mitochon-dria and activity of superoxides dismutase(SOD)was studied. Myocardial mitochondrial functionwas depressed slightly 60 rain after ischemia but significantly 60 min after reperfusion.Increasedlipid peroxides content and decreased activity of SOD were observed at 60 rain after ischemia.Af-ter reperfusion,the activity of SOD continued decreasing,and LPO elevated still further.Theseresults support the hypothesis that free radicals may contribute to myocardial reperfusion injury. |
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Myocardial mitochondrial functionwas depressed slightly 60 rain after ischemia but significantly 60 min after reperfusion.Increasedlipid peroxides content and decreased activity of SOD were observed at 60 rain after ischemia.Af-ter reperfusion,the activity of SOD continued decreasing,and LPO elevated still further.Theseresults support the hypothesis that free radicals may contribute to myocardial reperfusion injury.</description><identifier>ISSN: 2095-7467</identifier><language>eng</language><subject>bypass ; cardiopulmonary ; cats ; dismutase ; heart ; ischemia ; mitochondria ; peroxides ; reperfusion ; superoxides</subject><ispartof>中国人民解放军军医大学学报：英文版, 1993 (4), p.337-341</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/84233X/84233X.jpg</thumbnail><link.rule.ids>314,776,780,4010</link.rule.ids></links><search><creatorcontrib>陈龙 张宝仁 朱家麟 陈如坤 郝家骅 陈晓晴 陈克明</creatorcontrib><title>Alterations of mitochondrial function in ischemia/reperfusion cat heart</title><title>中国人民解放军军医大学学报：英文版</title><addtitle>Journal of Medical Colleges of PLA(China)</addtitle><description>The effect of myocardium being subjected to 60 min ischemia and 60 min reperfusion incat cardiopulmonary bypass on level of lipid peroxides(LPO),function of myocardial mitochon-dria and activity of superoxides dismutase(SOD)was studied. 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| identifier | ISSN: 2095-7467 |
| ispartof | 中国人民解放军军医大学学报：英文版, 1993 (4), p.337-341 |
| issn | 2095-7467 |
| language | eng |
| recordid | cdi_chongqing_primary_4001521822 |
| source | Alma/SFX Local Collection |
| subjects | bypass cardiopulmonary cats dismutase heart ischemia mitochondria peroxides reperfusion superoxides |
| title | Alterations of mitochondrial function in ischemia/reperfusion cat heart |
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